Browsing by Author "201-0435872"

Now showing items 1-9 of 9

    • Analysis of the opioid–opioid combinations according to the nociceptive stimulus in mice 
      Romero, Asunción; Miranda Guzmán, Hugo; Puig, Margarita M. (ELSEVIER, 2010)
      The purpose of the present study was to characterize the antinociceptive effects of tramadol, fentanyl and morphine,whentwoofthemwere systemically combined in a 1:1 potency ratio, in the hot plate, the acetic acid writhing, ...
    • Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice 
      Arrau, Sylvia; Delporte Vergara, Carla; Cartagena, Carlos; Rodríguez Díaz, Maité; González, Patricia; Silva, Ximena; Cassels Niven, Bruce; Miranda Guzmán, Hugo (Elsevier, 2011-01-07)
      Ethnopharmacological relevance: Quillaja saponaria bark contains a high percentage of triterpene saponins and has been used for centuries as a cleansing and analgesic agent in Chilean folk medicine. Aim of the study: The ...
    • Antinociceptive Synergism of Gabapentin and Nortriptyline in Mice with Partial Sciatic Nerve Ligation 
      Miranda Guzmán, Hugo; Noriega, Viviana; Zepeda Iriarte, Ramiro; Zanetta, Pilar; Prieto Rayo, Josefina; Prieto Domínguez, Juan; Sierralta, Fernando (Karger, 2015)
      Background and Methods: Neuropathic pain results from nerve injury, and gabapentin, an antiepileptic drug, has been approved for the treatment of several types of neuropathic pain. On the other hand, nortriptyline, an ...
    • Corrigendum to “Pharmacological profile of dexketoprofen in orofacial pain” [Pharmacol. Rep. 68 (6) (2016) ... 
      Miranda Guzmán, Hugo; Sierralta García, Fernando; Aranda, Nicolás; Noriega, Viviana; Prieto Dominguez, Juan Carlos (Elsevier, 2018)
    • Involvement of NO in antinociception of NSAIDS in murine formalin hind paw assay 
      Noriega Sepúlveda, Viviana; Miranda Guzmán, Hugo; Prieto Domínguez, Juan Carlos; Sotomayor Zárate, Ramón; Sierralta García, Fernando (Thieme, 2020)
      There are different animal models to evaluate pain among them the formalin hind paw assay which is widely used since some of its events appear to be similar to the clinical pain of humans. The assay in which a dilute ...
    • Isobolographic analysis of the opioid-opioid interactions in a tonic and a phasic mouse model of induced ... 
      Miranda Guzmán, Hugo; Noriega, Viviana; Zanetta, Pilar; Prieto Domínguez, Juan; Prieto Rayo, Juan Carlos; Aranda, Nicolás; Sierralta García, Fernando (BioMed Central, 2014)
      Background: Opioids have been used for the management of pain and coadministration of two opioids may induce synergism. In a model of tonic pain, the acetic acid writhing test and in a phasic model, the hot plate, ...
    • Pharmacological profile of dexketoprofen in orofacial pain 
      Miranda Guzmán, Hugo; Sierralta García, Fernando; Aranda Ortega, Nicolás; Noriega Sepúlveda, Viviana; Prieto Domíngez, Juan Carlos (Elsevier, 2016)
      Background: Non-steroidal anti-inflammatory drugs (NSAIDs) may act through others mechanisms, in addition to inhibition of prostaglandin synthesis. These includes cholinergic, NO, serotonergic and opioids pathways. ...
    • Receptors involved in dexketoprofen analgesia in murine visceral pain 
      Noriega Sepúlveda, Viviana Carolina; Sierralta García, Fernando; Poblete, P.; Aranda, N.; Sotomayor Zárate, R; Prieto Domínguez, Juan Carlos; Miranda Guzmán, Hugo (Indian Academy of Sciences, 2020)
      Various animal models, especially rodents, are used to study pain, due to the difficulty of studying it in humans. Many drugs that produce analgesia have been studied and there is evidence among which NSAIDs deserve to be ...
    • The Antinociceptive Activities of Certain NSAIDS Combinations in Murine Orofacial Test 
      Miranda Guzmán, Hugo; Noriega Sepúlveda, Viviana; Sierralta García, Fernando; Sotomayor Zárate, Ramón; Prieto Domínguez, Juan Carlos (Georg Thieme Verlag KG, 2020)
      Pain models are mostly in rodents and between them formalin orofacial test allow discrimination among antinociception and anti-inflammation. This assay use a formalin solution injected into the upper right lip of each mouse ...