Browsing by Author "201-0461786"

Now showing items 1-14 of 14

    • Aberrant MUC1 accumulation in salivary glands of Sjogren's syndrome patients is reversed by TUDCA in vitro 
      Castro Masso, Isabel; Albornoz, Nicolás; Aguilera, Sergio; Barrera, María José; González, Sergio; Núñez, Matilde; Carvajal, Patricia; Jara, Daniela; Lagos, Carolina; Molina, Claudio; Urzúa Tobar, Ulises; Hermoso, Marcela; González Burgos, María Julieta (Oxford University Press, 2020)
      Objectives. Xerostomia in SS patients has been associated with low quality and quantity of salivary mucins, which are fundamental for the hydration and protection of the oral mucosa. The aim of this study was to evaluate ...
    • Alterations in Type I Hemidesmosome Components Suggestive of Epigenetic Control in the Salivary Glands of ... 
      González, Sergio; Aguilera, Sergio; Alliende, Cecilia; Urzúa Tobar, Ulises; Quest, Andrew F. G.; Herrera Cisterna, Luisa; Molina, Claudio; Hermoso Ramello, Marcela; Ewert, Patricia; Brito, Mónica; Romo, Rafael; Leyton Martínez, Cecilia; Pérez, Paola; González Burgos, María Julieta (2011-04)
      Objective. Acinar cells in the salivary glands of patients with Sjo¨gren’s syndrome (SS) display severe alterations in anchorage to the basal lamina. Bioinformatics analysis of the BP230 gene sequence has revealed the ...
    • Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in ... 
      Castro, Isabel; Aguilera, Sergio; Brockhausen, Inka; Alliende, Cecilia; Quest, Andrew F. G.; Molina, Claudio; Urzúa Tobar, Ulises; Mandel, Ulla; Bahamondes, Verónica; Barrera, María José; Sánchez, Marianela; González, Sergio; Hermoso Ramello, Marcela; Leyton Martínez, Cecilia; González Burgos, María Julieta (Oxford University Press, 2012)
      Objectives. To determine the expression and enzymatic activities of sulphotransferases involved in mucin hyposulphation in labial salivary glands (LSGs) from SS patients and to correlate sulphotransferase activity with ...
    • Gene expression and chromosomal location for susceptibility to Sjögren's syndrome 
      Pérez, Paola; Anaya, Juan Manuel; Aguilera, Sergio; Urzúa Tobar, Ulises; Munroe, David; Molina, Claudio; Hermoso Ramello, Marcela; Cherry, James Michael; Alliende, Cecilia; Olea, Nancy; Ruiz-Narváez, Edward; González Burgos, María Julieta (2009)
      Primary Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disease affecting mainly the exocrine glands. Its physio-pathology is poorly understood and most of the knowledge has been related to the inflammatory ...
    • Genomic and phenotypic comparison between similar wine yeast strains of Saccharomyces cerevisiae from ... 
      Salinas, F.; Mandakovic Seyler, Dinka; Urzúa Tobar, Ulises; Massera, A.; Miras, S.; Combina, M.; Ganga, M. Angélica; Martínez, C. (2010)
      Aims: To study genomic and phenotypic changes in wine yeasts produced in short time periods analysing yeast strains possibly derived from commercial strains recently dispersed. Methods and Results: We conducted a genomic ...
    • Global transcriptomic analysis uncovers a switch to anaerobic metabolism in tellurite-exposed Escherichia coli 
      Molina Quiroz, Roberto; Loyola, David E.; Díaz Vásquez, Waldo A.; Arenas, Felipe A.; Urzúa Tobar, Ulises; Pérez Donoso, José; Vásquez, Claudio C. (Elsevier Masson SAS, 2014)
      © 2014 Institut Pasteur. Tellurite (TeO32-) is harmful for most microorganisms, especially Gram-negative bacteria. Even though tellurite toxicity involves a number of individual aspects, including oxidative stress, ...
    • Identification of genes related to nitrogen uptake in wine strains of Saccharomyces cerevisiae 
      Contreras, A.; García, V.; Salinas, F.; Urzúa Tobar, Ulises; Ganga, M. A.; Martínez, C. (Springer, 2012)
      The yeast Saccharomyces cerevisiae is the main microorganism responsible for wine fermentation and its development influences the quality of wine. A problem affecting these types of fermentations, generating important losses ...
    • Increased expression of p2ry2, cd248 and ephb1 in gastric cancers from chilean patients 
      Aquea, Gisela; Bresky, Gustavo; Lancellotti, Domingo; Madariaga, Juan Andrés; Zaffiri, Vittorio; Urzúa Tobar, Ulises; Haberle, Sergio; Bernal, Giuliano (National Cancer Center, 2014)
      Background: Gastric cancer (GC) ranks as one of the major causes of mortality due to cancer worldwide. In Chile, it is currently the leading cause of cancer death. Identification of novel molecular markers that may help ...
    • Oral dryness in Sjögren's syndrome patients. Not just a question of water 
      Castro, I.; Sepúlveda, D.; Cortés, J.; Quest, Andrew F. G.; Barrera, M. J.; Bahamondes, V.; Aguilera, S.; Urzúa Tobar, Ulises; Alliende, C.; Molina, C.; González, S.; Hermoso Ramello, Marcela; Leyton Blanca, Cristina; González, M. J. (Elsevier, 2013)
      Sjögren's syndrome (SS) is a chronic autoimmune disease of undefined etiology. Patients with this syndromesuffer from severe alterations in both the quality and quantity of saliva and tears, due to impaired function of ...
    • Oxidative stress in female cancers 
      Calaf, Gloria M.; Urzúa Tobar, Ulises; Termini, Lara; Aguayo, Francisco (Impact Journals LLC, 2018)
      © Calaf et al. Breast, cervical and ovarian cancers are highly prevalent in women worldwide. Environmental, hormonal and viral-related factors are especially relevant in the development of these tumors. These factors are ...
    • Parity history determines a systemic inflammatory response to spread of ovarian cancer in naturally aged mice 
      Urzúa Tobar, Ulises; Chacón, Carlos; Lizama, Luis; Sarmiento, Sebastián; Villalobos, Pía; Kroxato, Belén; Marcelain Cubillos, Katherine; González Burgos, María Julieta (International Society on Aging and Disease, 2017)
      Aging intersects with reproductive senescence in women by promoting a systemic low-grade chronic inflammation that predisposes women to several diseases including ovarian cancer (OC). OC risk at menopause is significantly ...
    • Ski Is required for tri-methylation of H3K9 in major satellite and for repression of pericentromeric genes: ... 
      Cappelli, Claudio; Sepúlveda, Hugo; Rivas Vera, Solange; Pola Véliz, Víctor; Urzúa Tobar, Ulises; Donoso Luna, Gerardo; Sagredo Campos, Eduardo; Carrero Zapata, David; Casanova Ortiz, Emmanuel; Sagredo Campos, Alfredo; González Vergara, Marisel; Manterola Zúñiga, Marcia; Nardocci, Gino; Armisén Yañez, Ricardo; Montecino, Martín; Marcelain Cubillos, Katherine (Elsevier, 2020)
      Several mechanisms directing a rapid transcriptional reactivation of genes immediately after mitosis have been described. However, little is known about the maintenance of repressive signals during mitosis. In this work, ...
    • Transcriptomic analysis of an in vitro murine model of ovarian carcinoma: Functional similarity to the human ... 
      Urzúa Tobar, Ulises; Roby, Katherine F.; Gangi, Lisa M.; Cherry, James M.; Powell, John I.; Munroe, David J. (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2006-03)
      Ovarian cancer is an aggressive disease of poor prognostic when detected at advanced stage. it is widely accepted that the ovarian surface epithelium plays a central role in disease etiology, but little is known about ...
    • Upregulation of PIR gene expression induced by human papillomavirus E6 and E7 in epithelial oral and cervical cells 
      Carrillo, Diego; Muñoz, Juan P.; Huerta, Hernán; Leal, Gabriel; Corvalán, Alejandro; León Decap, Óscar; Calaf, Gloria M.; Urzúa Tobar, Ulises; Boccardo, Enrique; Tapia Pineda, Julio; Aguayo González, Francisco (Royal Soc., 2017)
      The hallmark of high-risk human papillomavirus (HR-HPV)-related carcinogenesis is E6 and E7 oncogene overexpression. The aim of this work was to characterize epithelial oral and cervical cancer cells that express HR-HPV ...