Browsing by Author "20a7c6cb-00ef-4a3c-aac4-aaeebb24458a"

Now showing items 1-2 of 2

    • Cell lines derived from hippocampal neurons of the normal and trisomy 16 mouse fetus (a model for Down ... 
      Cárdenas, Ana María; Arriagada, Christian; Allen, David D.; Caviedes, Raúl; Cortes, José F.; Martin, José; Couve, Eduardo; Rapoport, Stanley I.; Shimahara, Takeshi; Caviedes, Pablo (Academic Press Inc., 2002)
      We have established hippocampal cell lines from normal and trisomy 16 fetal mice, a model of human trisomy 21. Both cell lines, named H1b (derived from a normal animal) and HTk (trisomic) possess neuronal markers by ...
    • Knockdown of Myo-Inositol transporter SMIT1 normalizes cholinergic and glutamatergic function in an ... 
      Cárdenas, Ana María; Fernández Olivares, Paola; Díaz Franulic, Ignacio; González Jamett, Arlek M.; Shimahara, Takeshi; Segura Aguilar, Juan; Caviedes Codelia, Raúl; Caviedes Fernández, Pablo (Springer, 2017)
      The Na+/myo-inositol cotransporter (SMIT1) is overexpressed in human Down syndrome (DS) and in trisomy 16 fetal mice (Ts16), an animal model of the human condition. SMIT1 overexpression determines increased levels of ...