Browsing by Author "21860954-53dd-4eff-92bd-8e1079cad27f"
Now showing items 1-7 of 7
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Moreno, Cristian; Hermosilla, Tamara; Hardy, Paulina; Aballai, Víctor; Rojas, Patricio; Varela Lekanda, Diego (MDPI, 2020)Functional and morphological modifications in the brain caused by major mood disorders involve many brain areas, including the hippocampus, leading to cognitive and mood alterations. Ca(v)1.2 channel expression has been ...
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Calcium-dependent inactivation controls cardiac L-type Ca2+ currents under β-adrenergic stimulation Morales, Danna; Hermosilla, Tamara; Varela, Diego (NLM (Medline), 2019)The activity of L-type calcium channels is associated with the duration of the plateau phase of the cardiac action potential (AP) and it is controlled by voltage- and calcium-dependent inactivation (VDI and CDI, respectively). ...
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Moreno, Cristian; Hermosilla, Tamara; Morales, Danna; Encina, Matías; Torres-Díaz, Leandro; Díaz, Pablo; Sarmiento, Daniela; Simon, Felipe; Varela, Diego (Springer Verlag, 2015)© 2015, Springer-Verlag Berlin Heidelberg.In the heart, the main pathway for calcium influx is mediated by L-type calcium channels, a multi-subunit complex composed of the pore-forming subunit CaV1.2 and the auxiliary ...
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Alarcón, Juan Marcos; Brito Jara, Julio; Hermosilla, Tamara; Atwater Ransom, Illani; Mears, David; Rojas, Eduardo (ELSEVIER, 2006-01)Incorporation of Alzheimer's disease amyloid beta-proteins (A beta Ps) across natural and artificial bilayer membranes leads to the formation of cation-selective channels. To study the peptide-membrane interactions involved ...
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Hermosilla, Tamara; Moreno, Cristian; Itfinca, Mircea; Altier, Christophe; Armisen Yáñez, Ricardo; Stutzin Schottlander, Andrés; Zamponi, Gerald W.; Varela, Diego (Taylor and Francis Inc., 2011)Angiotensin II regulation of L-type calcium currents in cardiac muscle is controversial and the underlying signaling events are not completely understood. Moreover, the possible role of auxiliary subunit composition of the ...
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Hermosilla, Tamara; Encina, Matías; Morales, Danna; Moreno, Cristian; Conejeros, Carolina; Alfaro Valdés, Hilda M.; Lagos Meza, Felipe; Simon, Felipe; Altier, Christophe; Varela, Diego (Nature Publishing Group, 2017)The cardiac L-type calcium channel is a multi-subunit complex that requires co-assembling of the pore-forming subunit Ca(V)1.2 with auxiliary subunits Ca-V alpha 2 delta and Ca-V beta. Its traffic has been shown to be ...
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Aguillón Gutiérrez, Juan Carlos; Harris, Robert; Molina, María Carmen; Colombo, Alicia; Cortés, Claudio; Hermosilla, Tamara; Carreño, Paz; Örn, Anders; Ferreira, Arturo (1997)If the H-2 congenic mouse strains A.SW (H-2(s)) and A.CA (H-2(f)), are infected with Trypanosoma cruzi, a 45 kDa protein (Tc45), present in cultured epimastigotes and blood trypomastigotes, is recognized only by the A.SW ...