Now showing items 21-40 of 54

    • Quintanilla González, María Elena; Ezquer, Fernando; Morales Retamales, Paola; Ezquer, Marcelo; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Wiley, 2020)
    • Ezquer, Fernando; Quintanilla González, María Elena; Morales, Paola; Santapau, Daniela; Ezquer, Marcelo; Kogan Bocian, Marcelo; Salas Huenuleo, Edison; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Blackwell Publishing Ltd, 2018)
      © 2018 Society for the Study of AddictionChronic ethanol consumption leads to brain oxidative stress and neuroinflammation, conditions known to potentiate and perpetuate each other. Several studies have shown that ...
    • Karahanian, Eduardo; Rivera Meza, Mario; Tampier de Jong, Lutske; Quintanilla González, María Elena; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Society for the Study of Addiction, 2014)
      Previous studies suggest that acetaldehyde generated from ethanol in the brain is reinforcing. The present studies tested the feasibility of achieving a long-term reduction of chronic and post-deprivation binge ethanol ...
    • Marriott, Amber L.; Rojas Mancilla, Edgardo; Morales Retamales, Paola; Herrera-Marschitz Muller, Mario; Tasker, R. Andrew (Elsevier, 2017-08)
      It is now well established that many of society’s most devastating and costly neurological diseases and disorders arise from trauma at, or shortly after birth. In some cases deficits are seen in childhood and in others ...
    • Tapia Bustos, A.; Pérez Lobos, R.; Vío, V.; Lespay Rebolledo, C.; Palacios, E.; Chiti-Morales, A.; Bustamante, D.; Herrera-Marschitz Muller, Mario; Morales, P. (Springer New York LLC, 2017)
      © 2016, Springer Science+Business Media New York. Perinatal asphyxia (PA) is associated to delayed cell death, affecting neurocircuitries of basal ganglia and hippocampus, and long-term neuropsychiatric disabilities. Several ...
    • Quintanilla González, María Elena; Ezquer, Fernando; Morales Retamales, Paola; Ezquer, Marcelo; Olivares, Belén; Santapau, Daniela; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Frontiers Media, 2020)
      Chronic ethanol intake results in brain oxidative stress and neuroinflammation, which have been postulated to perpetuate alcohol intake and to induce alcohol relapse. The present study assessed the mechanisms involved in ...
    • Romero, César A.; Bustamante, Diego; Zapata Torres, Gerald Amilcar; Goiny, Michel; Cassels Niven, Bruce; Herrera-Marschitz Muller, Mario (F P GRAHAM PUBLISHING CO, 2006-08)
      The clinical utility of amphetamine and amphetamine analogues has been jeopardized by a number of side effects and toxicity, partly due to complex mechanisms of action. While some of the analogues have been individually ...
    • Bustamante, Diego; Morales Retamales, Paola; Torres Pereyra, Francisco; Goiny, Michel; Herrera-Marschitz Muller, Mario (Springer-Verlag, 2007)
      The present study shows that nicotinamide prevents the long-term eVect of perinatal asphyxia on dopamine release monitored with in vivo microdialysis in the neostriatum of 3-month-old rats. Perinatal asphyxia was induced ...
    • Morales, Paola; Simola, Nicola; Bustamante, Diego; Lisboa, Francisco; Fiedler, Jenny; Gebicke Haerter, Peter J.; Morelli, Micaela; Tasker, R. Andrew; Herrera-Marschitz Muller, Mario (2010)
      There is no established treatment for the long-term effects produced by perinatal asphyxia. Thus, we investigated the neuroprotection provided by nicotinamide against the effects elicited by perinatal asphyxia on hippocampus ...
    • Bustamante, D.; Goiny, M.; Åström, G.; Gross, J.; Andersson, K.; Herrera-Marschitz Muller, Mario (2003)
      Asphyxia during birth can cause gross brain damage, but also subtle perturbations expressed as biochemical or motor deficits with late onset in life. Thus, it has been shown that brain dopamine levels can be increased or ...
    • Morales Retamales, Paola; Simola, Nicola; Bustamante, Diego; Lisboa, Francisco; Fiedler Temer, Jenny; Gebicke Haerter, Peter J.; Morelli, Micaela; Tasker, R. Andrew; Herrera-Marschitz Muller, Mario (Springer, 2010)
      There is no established treatment for the longterm eVects produced by perinatal asphyxia. Thus, we investigated the neuroprotection provided by nicotinamide against the eVects elicited by perinatal asphyxia on hippocampus ...
    • Herrera-Marschitz Muller, Mario (SPRINGER, 2006-11)
    • Rivera Meza, Mario; Quintanilla González, María Elena; Bustamante Cádiz, Diego; Delgado Arriagada, Ricardo; Buscaglia Fernández, Marianne; Herrera-Marschitz Muller, Mario (Research Society on Alcoholism, 2014)
      Background: A number of studies have shown that ethanol (EtOH) activates dopamine neurocircuitries and is self-administered into the ventral tegmental area (VTA) of the rat brain. In vitro and in silico studies have ...
    • Morales, P.; Klawitter, V.; Johansson, S.; Huaiquín, P.; Barros, V. G.; Ávalos, Ana María; Fiedler Temer, Jenny; Bustamante, D.; Gómez Urquijo, Sonia; Goiny, Michel; Herrera-Marschitz Muller, Mario (ELSEVIER SCI IRELAND LTD, 2003-09-18)
      The effect of perinatal asphyxia on brain development was studied with organotypic cultures from substantia nigra, neostriatum and neocortex. Asphyxia was induced by immersing foetuses-containing uterine horns removed from ...
    • Morales, P.; Huaiquín, P.; Bustamante, D.; Fiedler Temer, Jenny; Herrera-Marschitz Muller, Mario (F.P. Graham Publishing Co., 2007)
      There is clinical and experimental evidence indicating that neurocircuitries of the hippocampus are vulnerable to hypoxia/ischemia occurring at birth, inducing, upon re-oxygenation/re-circulation, delayed neuronal ...
    • Neira Peña, T.; Rojas Mancilla, E.; Muñoz Vio, V.; Pérez, R.; Gutiérrez Hernández, M.; Bustamante, D.; Morales, P.; Hermoso, M. A.; Gebicke-Haerter, P.; Herrera-Marschitz Muller, Mario (Springer New York LLC, 2015)
      © 2015, The Author(s).Perinatal asphyxia (PA) is a leading cause of neuronal damage in newborns, resulting in long-term neurological and cognitive deficits, in part due to impairment of mesostriatal and mesolimbic ...
    • Herrera-Marschitz Muller, Mario; Neira-Pena, Tanya; Rojas-Mancilla, Edgardo; Espina Marchant, Pablo; Esmar, Daniela; Perez, Ronald; Muñoz, Valentina; Gutierrez-Hernandez, Manuel; Rivera, Benjamin; Simola, Nicola; Bustamante, Diego; Morales, Paola; Gebicke-Haerter, Peter J. (Frontiers Research Foundation, 2014)
      Perinatal asphyxia constitutes a prototype of obstetric complications occurring when pulmonary oxygenation is delayed or interrupted. The primary insult relates to the duration of the period lacking oxygenation, leading ...
    • Herrera-Marschitz Muller, Mario; Morales Retamales, Paola; Leyton Campos, Lisette; Bustamante, Diego; Klawitter, Verena; Espina Marchant, Pablo; Allende, Camilo; Lisboa, Francisco; Cunich, Gabriel; Jara Cavieres, Antonella; Neira, Tanya; Gutiérrez Hernández, Manuel A.; González Lira, Víctor; Simola, Nicola; Schmitt, Andrea; Morelli, Micaela; Tasker, R. Andrew; Gebicke Haerter, Peter J. (Springer, 2011)
      Delivery is a stressful and risky event menacing the newborn. The mother-dependent respiration has to be replaced by autonomous pulmonary breathing immediately after delivery. If delayed, it may lead to deficient ...
    • Klawitter, Verena; Morales Retamales, Paola; Bustamante, Diego; Gómez Urquijo, Sonia; Hokfelt, Tomas; Herrera-Marschitz Muller, Mario (SPRINGER, 2007-06)
      The potential neuroprotection of nicotinamide on the consequences of perinatal asphyxia was investigated with triple organotypic cultures. Perinatal asphyxia was induced in vivo by immersing foetuses-containing uterine ...
    • Morales, P.; Fiedler Temer, Jenny; Andrés, S.; Berrios, C.; Huaiquín, P.; Bustamante, D.; Cárdenas, S.; Parra, E.; Herrera-Marschitz Muller, Mario (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-09)
      Asphyxia during delivery produces long-term deficits in brain development, including hippocampus. We investigated hippocampal plasticity after perinatal asphyxia, measuring postnatal apoptosis and neurogenesis. Asphyxia ...