Browsing by Author "27dfff39-8bbb-4f64-9f2d-2a51a2c57945"
Now showing items 1-9 of 9
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Maldonado, Edio; Cabrejos, María Eugenia; Banks, Lawrence; Allende, Jorge E. (2002)Previous studies have shown that the HPV-1 6 E7 protein interacts with TBP. This interaction was found to take place through residues in the carboxy terminal half of E7, mutation of which resulted in weaker transforming ...
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Mosquera, Jocelyn; Armisen Yáñez, Ricardo; Zhao, Hongling; Rojas, Diego A.; Maldonado, Edio; Tapia, Julio C.; Colombo, Alicia; Hayman, Michael J.; Marcelain Cubillos, Katherine (2011)Ski is a negative regulator of the transforming growth factor-β and other signalling pathways. The absence of SKI in mouse fibroblasts leads to chromosome segregation defects and genomic instability, suggesting a role for ...
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Yue, Zhenyu; Maldonado, Edio; Pillutla, Renuka; Cho, Helen; Reinberg, Danny; Shatkin, Aaron J. (1997)5'-Capping is an early mRNA modification that has important consequences for downstream events in gene expression. We have isolated mammalian cDNAs encoding capping enzyme. They contain the sequence motifs characteristic ...
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Eltit Ortega, José Miguel; García, Alejandra; Hidalgo, Jorge; Liberona, José L.; Chiong Lay, Mario; Lavandero González, Sergio; Maldonado, Edio; Jaimovich Pérez, Enrique (American Society for Biochemistry and Molecular Biology Inc., 2006)Tetanic electrical stimulation of myotubes evokes a ryanodine receptor-related fast calcium signal, during the stimulation, followed by a phospholipase C/inositol 1,4,5-trisphosphate-dependent slow calcium signal few seconds ...
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Pillutla, Renuka C.; Yue, Zhenyu; Maldonado, Edio; Shatkin, Aaron J. (1998)Guanine N-7 methylation is an essential step in the formation of the m7GpppN cap structure that is characteristic of eukaryotic mRNA 5' ends. The terminal 7-methylguanosine is recognized by cap-binding proteins that ...
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Maldonado, Edio; Hampsey, Michael; Reinberg, Danny (Cell Press, 1999)
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Montes, Matías; Moreira Ramos, Sandra; Rojas, Diego A.; Urbina, Fabiola; Käufer, Norbert F.; Maldonado, Edio (Blackwell Publishing Ltd, 2017)© 2017 Federation of European Biochemical Societies In Schizosaccharomyces pombe, ribosomal protein gene (RPG) promoters contain a TATA box analog, the HomolD box, which is bound by the Rrn7 protein. Despite the importance ...
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Rojas, Diego A.; Moreira-Ramos, Sandra; Zock-Emmenthal, Susanne; Urbina, Fabiola; Contreras-Levicoy, Juan; Käufer, Norbert F.; Maldonado, Edio (2011)The region in promoters that specifies the transcription machinery is called the core promoter, displaying core promoter elements (CPE) necessary for establishment of a preinitiation complex and the initiation of transcription. ...
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Contreras-Levicoy, Juan; Moreira-Ramos, Sandra; Rojas, Diego A.; Urbina, Fabiola; Maldonado, Edio (2012)TATA box is the most studied core promoter element and has a well-described transcription mechanism. However, most metazoan promoters lack TATA box and contain other core promoter elements. One of such elements is HomolD ...