Browsing by Author "2a0f9beb-9e12-45e1-aae7-f297bd514b23"
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Asela, I.; Noyong, M.; Simon, U.; Andrades Lagos, Juan Andrés; Campanini Salinas, J.; Vásquez Velásquez, David; Kogan Bocian, Marcelo; Yutronic Sáez, Nicolás; Sierpe, R. (Public Library Science, 2017)While 2-amino-4-(4-chlorophenyl)thiazole (AT) drug and thiazole derivatives have several biological applications, these compounds present some drawbacks, such as low aqueous solubility and instability. A new complex of ...
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Nitrofuran drugs beyond redox cycling: Evidence of Nitroreduction-independent cytotoxicity mechanism Gallardo Garrido, C.; Cho, Y.; Cortés Ríos, J.; Vásquez Velásquez, David; Pessoa Mahana, C. David; Araya Maturana, R.; Pessoa Mahana, Hernán; Faúndez, M. (Elsevier, 2020)Nitrofurans (5-nitro-2-hydrazonylfuran as pharmacophore) are a group of widely used antimicrobial drugs but also associated to a variety of side effects. The molecular mechanisms that underlie the cytotoxic effects of ...