Now showing items 1-9 of 9

    • Aravena, Octavio; Pesce Reyes, Bárbara; Soto, Lilian; Orrego, Natalia; Sabugo, Francisca; Wurmann, Pamela; Molina, María Carmen; Alfaro, Jorge; Cuchacovich Turteltaub, Miguel; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego (2011)
      The aim of this work was to study the effect of anti-TNF treatment on CD4+ Th1, Th17 and regulatory T cells (Tregs), together with CD8+ T cells and NK cells from rheumatoid arthritis (RA) patients. For this purpose, 18 RA ...
    • Martínez, S.; Berríos, S.; Fernández Donoso, Raúl; Brahm, J.; Cuchacovich Turteltaub, Miguel (1996)
      Antimitochondrial antibodies (AMA) are characteristically present in the serum of patients with primary biliary cirrhosis (PBC). AMA detection constitutes an important step for the clinical diagnosis of PBC, the indirect ...
    • Catalán Martina, Diego; Aravena, Octavio; Sabugo, Francisca; Wurmann, Pamela; Soto, Lilian; Kalergis, Alexis M.; Cuchacovich Turteltaub, Miguel; Aguillón Gutiérrez, Juan Carlos (2010)
      Introduction: Several molecules help preserve peripheral B cell tolerance, but when altered, they may predispose to autoimmunity. This work studied the expression of the costimulatory molecule CD86 and the inhibitory ...
    • Pesce Reyes, Bárbara; Soto Sáez, Lilian; Sabugo Siraqyan, María Francisca; Wurmann Kiblisky, Pamela; Cuchacovich Turteltaub, Miguel; López Nitsche, Mercedes; Sotelo, P. H.; Molina Sampayo, María Carmen; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego (2013)
      A new paradigm has emerged relating the pathogenesis of rheumatoid arthritis (RA), focused on the balance between T helper type 17 cells and regulatory T cells (Tregs). In humans, both subpopulations depend on ...
    • González Aguilar, A.; Villarroel Espíndola, Franz; Asenjo, J.; Francos, Rina; Cuchacovich Turteltaub, Miguel; Concha, I. I.; González Gronow, Mario; Slebe, Juan C. (Wiley, 2017)
    • Salazar, L.; Aravena, O.; Abello, P.; Escobar, A.; Contreras Levicoy, Juan; Rojas Colonelli, Nicole; Catalán Martina, Diego; Aguirre A., Luz María; Zúñiga, R.; Pesce Reyes, Bárbara; González, C.; Cepeda, R.; Cuchacovich Turteltaub, Miguel; Molina, M. C.; Salazar Onfray, Flavio; Delgado, M.; Toes, R. E.; Aguillón Gutiérrez, Juan Carlos (2008)
      Background: The use of regulatory or immature dendritic cells (DCs) as tools for modulating experimental rheumatoid arthritis is very recent. Tumour necrosis factor (TNF)-stimulated DCs have been shown to restore tolerance ...
    • García González, Paulina; Schinnerling, Katina; Sepúlveda Gutiérrez, Alejandro; Maggi, Jaxaira; Hoyos, Lorena; Morales, Rodrigo; Mehdi, Ahmed; Nel, Hendrik; Soto Sáez, Lilian; Pesce Reyes, Bárbara; Molina Sampayo, María Carmen; Cuchacovich Turteltaub, Miguel; Larrondo Lillo, Milton; Neira, Oscar; Catalán Martina, Diego; Hilkens, Catharien M.; Thomas, Ranjeny; Verdugo Salgado, Ricardo; Aguillón Gutiérrez, Juan Carlos (Frontiers Media, 2016-10-25)
      Tolerogenic dendritic cells (TolDCs) are promising tools for therapy of autoimmune diseases, such as rheumatoid arthritis (RA). Here, we characterize monocyte-derived TolDCs from RA patients modulated with dexamethasone ...
    • Cuchacovich Turteltaub, Miguel; Soto, L.; Edwardes, M.; Gutiérrez, M.; Llanos, C.; Pacheco, D.; Sabugo Siraqyan, María Francisca; Alamo, M.; Fuentealba, C.; Villanueva, L.; Gatica, H.; Schiattino, Irene; Salazar, L.; Catalán Martina, Diego; Valenzuela, O.; Salazar Onfray, Flavio; Aguillón Gutiérrez, Juan Carlos (2006)
      Objective: To investigate the influence of -308 tumour necrosis factor-α (TNFα) promoter polymorphism and circulating TNFα levels in the clinical response to adalimumab treatment in patients with rheumatoid arthritis (RA). ...
    • Cuchacovich Turteltaub, Miguel; Ferreira, L.; Aliste, M.; Soto, L.; Cuenca, J.; Cruzat, A.; Gatica, H.; Schiattino, Irene; Pérez, C.; Aguirre A., Luz María; Salazar Onfray, Flavio; Aguillón Gutiérrez, Juan Carlos (2004)
      Objective: To investigate the influence of -308 tumour necrosis factor-α (TNF-α) promoter polymorphism and circulating TNF-α levels in the clinical response to the infliximab treatment in patients with rheumatoid arthritis ...