Browsing by Author "32701088-633a-40d6-8124-ea6bc9f5e8ed"

Now showing items 1-4 of 4

    • Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca2+ ... 
      Cárdenas, César; Lovy, Alenka; Silva Pavéz, Eduardo; Urra Faúndez, Félix; Mizzoni, Craig; Ahumada Castro, Ulises; Bustos, Galdo; Jaña, Fabián; Cruz, Pablo; Farías, Paula; Mendoza, Elizabeth; Huerta, Hernán; Murgas, Paola; Hunter, Martín; Ríos, Melany; Cerda Arancibia, Oscar; Georgakoudi, Irene; Zakarian, Armen; Molgó, Jordi; Foskett, James Kevin (AAAS. American Association for the Advancement of Science, 2020)
      Spontaneous Ca2+ signaling from the InsP(3)R intracellular Ca2+ release channel to mitochondria is essential for optimal oxidative phosphorylation (OXPHOS) and ATP production. In cells with defective OXPHOS, reductive ...
    • Fibrinogen-clotting enzyme, pictobin, fromBothrops pictus snake venom. Structural and functional characterization 
      Vivas Ruiz, Dan E.; Sandoval, Gustavo A.; González Kozlova, Edgar; Zarria Romero, Jacquelyne; Lazo, Fanny; Rodríguez, Edith; Magalhães, Henrique; Chávez Olortegui, Carlos; Oliveira, Luciana S.; Alvarenga, Valeria G.; Urra Faúndez, Félix; Toledo, Jorge; Yarlequé, Armando; Eble, Johannes A.; Sánchez, Eladio F. (Elsevier, 2020)
      A thrombin-like enzyme, pictobin, was purified from Bothrops pictus snake venom. It is a 41-kDa monomeric glycoprotein as showed by mass spectrometry and contains approx. 45% carbohydrate by mass which could be removed ...
    • Idiopathic inflammatory myopathy human derived cells retain their ability to increase mitochondrial function 
      Basualto Alarcón, Carla; Urra, Félix; Bozán, María Francisca; Jaña, Fabián; Trangulao, Alejandra; Bevilacqua, Jorge A.; Cárdenas, J. César (Public Library Science, 2020)
      Idiopathic Inflammatory Myopathies (IIMs) have been studied within the framework of autoimmune diseases where skeletal muscle appears to have a passive role in the illness. However, persiting weakness even after resolving ...
    • Remodelamiento metabólico en células de cáncer de mama: rol de la bioenergética mitocondrial en la proliferación ... 
      Urra Faúndez, Félix A. (Universidad de Chile, 2016)
      El cáncer de mama es el cáncer más frecuentemente diagnosticado y la principal causa de muerte en mujeres en el mundo. Este cáncer es una enfermedad heterogénea compuesta por varios sub-tipos biológicamente distintos, en ...