Browsing by Author "3afed8b8-69ff-47b5-9bad-041232194322"

Now showing items 1-3 of 3

    • Continuous flow synthesis of lipophilic cations derived from benzoic acid as new cytotoxic chemical entities ... 
      Catalán Díaz, Mabel Elizabeth; Castro Castillo, Vicente; Gajardo de la Fuente, Javier; Aguilera, Jocelyn; Ferreira, Jorge; Ramires Fernández, Ricardo; Olmedo Alegría, Ivonne Odette; Molina Berríos, Alfredo Enrique; Palominos, Charlotte; Valencia, Marcelo; Domínguez, Marta; Souto, José A.; Jara Sandoval, José (Royal Society of Chemistry, 2020)
      Continuous flow chemistry was used for the synthesis of a series of delocalized lipophilic triphenylphosphonium cations (DLCs) linked by means of an ester functional group to several hydroxylated benzoic acid derivatives ...
    • The Microbiota-Derived Metabolite of Quercetin, 3,4-Dihydroxyphenylacetic Acid Prevents Malignant Transformation ... 
      Catalán Díaz, Mabel; Ferreira, Jorge; Carrasco Pozo, Catalina (MDPI, 2020)
      Meat diet plays a pivotal role in colorectal cancer (CRC). Hemin, a metabolite of myoglobin, produced after meat intake, has been involved in CRC initiation. The compound, 3,4-dihydroxyphenylacetic acid (3,4HPAA) is a ...
    • Trypanosoma cruzi: In vitro effect of aspirin with nifurtimox and benznidazole 
      López Muñoz, Rodrigo; Faúndez, Mario; Klein, Sebastián; Escanilla, Sebastián; Torres, Gloria; Lee-Liu, Dasfne; Ferrada Parker, Jorge; Kemmerling Weis, Ulrike; Orellana Bown, Myriam; Morello Casté, Antonio; Ferreira, Arturo; Maya Arango, Juan (ELSEVIER, 2010)
      Nifurtimox and benznidazole are the only active drugs against Trypanosoma cruzi; however, they have limited efficacy and severe side effects. During primoinfection, T. cruzi infected macrophages mount an antiparasitic ...