Browsing by Author "4026737b-6a2b-4c74-88eb-83712186b609"

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Artículo

Adaptation to milking agropastoralism in Chilean goat herders and nutritional benefit of lactase persistence

Montalva, Nicolás; Adhikari, Kaustubh; Liebert, Anke; Mendoza Revilla, Javier; Flores, Sergio V.; Mace, Ruth; Swallow, Dallas M. (Wiley, 2019)

The genetic trait of lactase persistence (LP) evolved as an adaptation to milking pastoralism in the Old World and is a well-known example of positive natural selection in humans. However, the specific mechanisms conferring ...
Artículo

Alcohol consumption patterns and genotypes determining alcohol tolerance in chilean university students ...

Silva, Constanza P.; Flores, Sergio V. (Sociedad Medica de Santiago, 2015)

© 2015 Sociedad Medica de Santiago. All rights reserved.Background: Alleles involved in inefficient (ADH1B2*2 and ALDH2*2) or efficient (SNP6, ADH4 gene) alcohol metabolism may influence the risk of alcoholism. Alcoholism ...
Artículo

Fixations of the HIV-1 env gene refute neutralism: New evidence for pan-selective evolution

Valenzuela, Carlos Y.; Flores, Sergio V.; Cisternas, Javier (Society of Biology of Chile, 2010)

We examined 103 nucleotide sequences of the HIV-1 env gene, sampled from 35 countries and tested: I) the random (neutral) distribution of the number of nucleotide changes; II) the proportion of bases at molecular equilibrium; ...
Artículo

Lactase Non-Persistence and General Patterns of Dairy Intake in Indigenous and Mestizo Chilean Populations

Fernández, Catalina I.; Montalva, Nicolás; Arias, Macarena; Hevia, Macarena; Moraga, Mauricio L.; Flores, Sergio V. (Wiley & Sons, 2016-03)

Objectives Lactase persistence (LP) is a genetic trait that has been studied among different countries and ethnic groups. In Latin America, the frequencies of this trait have been shown to vary according to the degree of ...