Browsing by Author "42feb4b7-84df-4ed6-8e42-1b0e78285431"
Now showing items 1-20 of 23
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Salgado, Francisco; Areche, Carlos; Sepúlveda, Beatriz; Simirgiotis, Mario J.; Cáceres, Fátima; Quispe, Cristina; Quispe, Lina; Cano, Teresa (Medknow Publications, 2014)Background: Azorella compacta is a rare yellow-green compact resinous cushion shrub growing from the high Andes of southern Peru to northwestern Argentina, and which is a producer of biologically active and unique diterpenoids. ...
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Absolute configuration of sargaol acetate using DFT calculations and vibrational circular dichroism Muñoz, Marcelo A.; Areche, Carlos; Rovirosa, Juana; San Martín Barrientos, Aurelio; Joseph-Nathan, Pedro (2010)The absolute configuration (AC) of sargaol acetate (2), isolated from the brown alga Stypopodium flabelliforme, was determined using vibrational circular dichroism (VCD) measurements and density functional theory (DFT) ...
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Muñoz, Marcelo A.; Areche, Carlos; Rovirosa, Juana; San Martín Barrientos, Aurelio; Gordillo Román, Bárbara; Joseph Nathan, Pedro (2012)The absolute configuration of alga meroditerpenoids (-)-taondiol diacetate (1b) and (+)-epitaondiol diacetate (2c) are assigned by vibrational circular dichroism (VCD). The spectra of (2S,3S,6R,7R,10R,11R,14S)-1b and ...
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Areche, Carlos; Sepúlveda, Beatriz; Martin, Aurelio San; García Beltrán, Olimpo; Simirgiotis, Mario J.; Cañete, Alvaro (Royal Society of Chemistry, 2014)Four new mulinane-type diterpenoids besides the known compounds mulin-11,13-dien-20-oic acid, 13α-hydroxyazorellane, 13β- hydroxyazorellane, mulinolic acid, azorellanol, and mulin-11,13-dien-18-acetoxy- 16,20-dioic acid ...
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Brito, Anghel; Areche, Carlos; Sepúlveda, Beatriz; Kennelly, Edward J.; Simirgiotis, Mario J. (MDPI AG, 2014)The anthocyanin composition and HPLC fingerprints of six small berries endemic of the VIII region of Chile were investigated using high resolution mass analysis for the first time (HR-ToF-ESI-MS). The antioxidant features ...
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Areche, Carlos; Zapata, Francisca; González, Mathias; Díaz, Esteban; Montecinos, Rubén; Hernández, Marcos; Melo, Francisco; Cornejo, Alberto (Wiley-VCH Verlag, 2019)Tau protein is a natively unfolded protein whose primary role is to participate in axonal transport closely associated with microtubules. Neurodegenerative disorders including Alzheimer's disease and Tauopathies involved ...
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Pereira, David M.; Cheel, Jose; Areche, Carlos; San Martín Barrientos, Aurelio; Rovirosa, Juana; Silva, Luis R.; Valentao, Patricia; Andrade, Paula B. (2011)The sea constitutes one of the most promising sources of novel compounds with potential application in human therapeutics. In particular, algae have proved to be an interesting source of new bioactive compounds. In this ...
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Guerrero-Castillo, Pedro; Reyes, Sarita; Robles, Juana; Simirgiotis, Mario J.; Sepulveda, Beatriz; Fernandez-Burgos, Ronald; Areche, Carlos (Elsevier Ltd, 2019)Pouteria lucuma fruit is widely used to prepare cakes, ice creams and juice or also commercialized as pulp and flour. As result of this business thousands of tons of seeds are generated as an agricultural waste. This study ...
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Areche, Carlos; Vaca Cerezo, Inmaculada; Labbe, Pamela; Soto Delgado, Jorge; Astudillo, Luis; Silva, Mario; Rovirosa, Juana; San Martín Barrientos, Aurelio (2011)Biological transformation of the meroditerpenoid, stypotriol triacetate (1) by the fungi Aspergillus niger, Cunninghamella elegans, Gibberella fujikuroi and Mucor plumbeus was studied. The incubation of 1 with A. niger ...
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Remonsellez, Francisco; Castro-Severyn, Juan; Pardo-Esté, Coral; Aguilar, Pablo; Fortt, Jonathan; Salinas, Cesar; Barahona, Sergio; León, Joice; Fuentes, Bárbara; Areche, Carlos; Hernández, Klaudia L.; Aguayo, Daniel; Saavedra, Claudia P. (Frontiers Media S.A., 2018)© 2007-2018 Frontiers Media S.A. All Rights Reserved. Poly-extremophiles microorganisms have the capacity to inhabit hostile environments and can survive several adverse conditions that include as variations in temperature, ...
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Simirgiotis, Mario J.; Vallejos, Javier; Areche, Carlos; Sepúlveda, Beatriz (MDPI AG, 2014)© 2014 by the authors; licensee MDPI, Basel, Switzerland. An enantioselective total synthesis of the natural amino acid (2S,4R,5R)-4,5-dihydroxy-pipecolic acid starting from D-glucoheptono-1, 4-lactone is presented. The ...
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García Beltrán, Olimpo; Areche, Carlos; Cassels Niven, Bruce; Cuca Suárez, Luis Enrique (Elsevier, 2014)
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Areche, Carlos; San Martín Barrientos, Aurelio; Rovirosa, Juana; Sepúlveda, Beatriz (2011)The effects of epitaondiol (1) and sargaol (2), isolated from the brown alga Stypopodium flabelliforme on HCl/ethanol-induced gastric lesions in mice were evaluated and compared with that of lansoprazole. Epitaondiol and ...
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Ardiles, Alejandro; Barrientos, Ruth; Simirgiotis, Mario J.; Bórquez, Jorge; Sepúlveda, Beatriz; Areche, Carlos (MDPI AG, 2018)© 2018 MDPI AG. All rights reserved. Forty-three metabolites including several methoxylated flavonoids, tremetones, and ent-clerodane diterpenes were accurately identified for the first time in the ethanolic extract of P. ...
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Brito, Anghel; Ramirez, Javier E.; Areche, Carlos; Sepúlveda, Beatriz; Simirgiotis, Mario J. (MDPI AG, 2014)© 2014 by the authors; licensee MDPI.Peels and edible pulp from three species of citrus including Citrus aurantifolia (varieties pica and sutil) and Citrus x lemon var. Genova widely cultivated and consumed in Northern ...
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Sepulveda, Beatriz; Chamy, Maria Cristina; Piovano, Marisa; Areche, Carlos (Sociedad Chilena de Quimica, 2013)Lichens are symbiotic relationship between fungi and algae or cyanobacteria. Secondary metabolites from lichens are known as lichen substances. We investigated depsidone and depside from lichens 1-6 in the context of their ...
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Torres-Benítez, Alfredo; Rivera-Montalvo, Mariá; Sepúlveda, Beatriz; Castro, Olivio N.; Nagles, Edgar; Simirgiotis, Mario J.; Garciá-Beltrán, Olimpo; Areche, Carlos (MDPI AG, 2017)© 2017 by the authors. Lichens are symbiotic associations of fungi with microalgae and/or cyanobacteria. Lichens belonging to the Parmeliaceae family comprise 2700 species of lichens, including the Parmotrema genus which ...
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Areche, Carlos; Fernández Burgos, Ronald; De Terrones, Teresa Cano; Simirgiotis, Mario; García Beltrán, Olimpo; Bórquez, Jorge; Sepúlveda, Beatriz (MDPI AG, 2019)Mulinum crassifolium Phil. (Apiaceae) is an endemic shrub from Chile commonly used as infusion in traditional medicine to treat diabetes, bronchial and intestinal disorders and stomach ailments, including ulcers. From the ...
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Cabañas García, Emmanuel; Areche, Carlos; Jáuregui Rincón, Juan; Cruz Sosa, Francisco; Pérez-Molphe Balch, Eugenio (MDPI AG, 2019)Chromatographic separation combined with mass spectrometry is a powerful tool for the characterization of plant metabolites because of its high sensitivity and selectivity. In this work, the phytochemical profile of aerial ...
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García Beltrán, Olimpo; Soto Delgado, Jorge; Iturriaga-Vásquez, Patricio; Areche, Carlos; Cassels Niven, Bruce (Sociedad Chilena de Quimica, 2012)The diene Erythrina alkaloids erysotrine (1), erysodine (2), erythraline (3), erytharbine (4), and erysotrine N-oxide (5), plus the hydroxylated dihydro derivative of 1, epierythratidine (6) were isolated from seeds of ...