Browsing by Author "4679026b-1db3-4a5a-8d3d-28c7100e7c7f"
Now showing items 1-4 of 4
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Cytoplasmic and nuclear STAT3 in GH-stimulated fibroblasts of children with idiopathic short stature Martínez Pinto, Jonathan; Salazar, Teresa; Ocaranza, Paula; Fuentes, Ariel; Román, Rossana; Cassorla Goluboff, Fernando (2010)Background: STAT5, which plays an important role in GH signal transduction, has been studied extensively in children with growth retardation, but there is scarce information regarding STAT3. Aim: We determined total and ...
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Ocaranza, Paula; Morales, Fernanda; Román, Rossana; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando (2012)Background/aim: Possible etiologies of idiopathic short stature (ISS) include a range of conditions, some of which may be caused by defects in the modulation of the growth hormone (GH)-signaling pathway. The Janus kinase/signal ...
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Ocaranza, Paula; Quintanilla González, María Elena; Tampier de Jong, Lutske; Karahanian, Eduardo; Sapag, Amalia; Israel Jacard, Yedy (2008)Background: Some gene polymorphisms strongly protect against the development of alcoholism. A large proportion of East Asians carry a protective inactivating mutation in aldehyde dehydrogenase (ALDH2*2). These subjects ...
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Ocaranza, Paula; Losekoot, Monique; Walenkamp, Marie J.E.; De Bruin, Christiaan; Wit, Jan M.; Mericq, Verónica (NLM (Medline), 2019)Objective: Insulin like growth factors-1 (IGF-1) is essential for normal in utero and postnatal human growth. It mediates its effects through the IGF-1 receptor (IGF1R), a widely expressed cell surface tyrosine kinase ...