Browsing by Author "474aa055-2d40-4e6a-8da7-e19c81285bc9"

Now showing items 1-13 of 13

    • A Materials Screening Test of Corrosion Monitoring in LiNO3 Containing Molten Salts as a Thermal Energy ... 
      Mallco, Abdiel; Portillo, Carlos; Kogan, Marcelo J.; Galleguillos, Felipe; Fernández, Ángel G. (MDPI, 2020)
      Featured Application: monitoring the effect of molten salt corrosion on materials used in solar thermal plants by means of electrochemical tests.
    • Chitosan-based nanoparticles for Intracellular delivery of ISAV fusion protein cDNA into melanoma cells: a ... 
      Robles Planells, Claudia; Sánchez-Guerrero, Giselle; Barrera Ávalos, Carlos; Matiacevich, Silvia; Rojo, Leonel E.; Pavéz, Jorge; Salas Huenuleo, Edison; Kogan, Marcelo J.; Escobar Álvarez, Alejandro; Milla, Luis A.; Fernández, Ricardo; Imarai, Mónica; Spencer, Eugenio; Huidobro Toro, Juan Pablo; Acuña Castillo, Claudio (Hindawi, 2020)
      Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation ...
    • Cohort profile: The Maule cohort (MAUCO) 
      Ferreccio, Catterina; Huidobro, Andrea; Cortés, Sandra; Bambs, Claudia; Toro, Pablo; Van De Wyngard, Vanessa; Acevedo, Johanna; Paredes, Fabio; Venegas, Pía; Verdejo, Hugo; Oyarzún González, Ximena; Cook, Paz; Castro, Pablo F.; Foerster, Claudia; Vargas, Claudio; Koshiol, Jill; Araya, Juan Carlos; Cruz, Francisco; Corvalán, Alejandro H.; Quest, Andrew F.; Kogan, Marcelo J.; Lavandero González, Sergio (Oxford University Press, 2020)
    • Cyclodextrin Nanosponges Inclusion Compounds Associated with Gold Nanoparticles for Potential Application ... 
      Venegas Salazar, Sebastián Nicolás; Yutronic Sáez, Nicolás; Kogan, Marcelo J.; Jara Vergara, Paul (MDPI, 2021)
      This article describes the synthesis and characterization of beta-cyclodextrin-based nano-sponges (NS) inclusion compounds (IC) with the anti-tumor drugs melphalan (MPH) and cytoxan (CYT), and the addition of gold nanoparticles ...
    • Exploiting the natural properties of extracellular vesicles in targeted delivery towards specific cells and tissues 
      Lara, Pablo; Chan, Alan B.; Cruz, Luis J.; Quest, Andrew F. G.; Kogan, Marcelo J. (MDPI, 2020)
      Extracellular vesicles (EVs) are important mediators of intercellular communication that participate in many physiological/pathological processes. As such, EVs have unique properties related to their origin, which can be ...
    • Gold Nanoparticles Mediate Improved Detection of beta-amyloid Aggregates by Fluorescence 
      Jara Guajardo, Pedro; Cabrera, Pablo; Celis, Freddy; Soler Jauma, Mónica; Berlanga Mora, Isadora; Parra Muñoz, Nicole; Acosta, Gerardo; Albericio, Fernando; Guzmán, Fanny; Campos, Marcelo; Álvarez, Alejandra; Morales Zavala, Francisco; Kogan, Marcelo J. (MDPI, 2020)
      The early detection of the amyloid beta peptide aggregates involved in Alzheimer's disease is crucial to test new potential treatments. In this research, we improved the detection of amyloid beta peptide aggregates in vitro ...
    • Inhibition of beta-amyloid Aggregation of Ugni molinae Extracts 
      Jara Moreno, Daniela; Riveros Salvatierra, Ana L.; Barriga G., Andrés; Kogan, Marcelo J.; Delporte Vergara, Carla (Bentham Science Publishers, 2020)
      The beta-amyloid peptide (1-42) is a molecule capable of aggregating into neurotoxic structures that have been implicated as potential etiological factors of Alzheimer's Disease. The aim of this study was to evaluate the ...
    • Inhibition of chymotrypsin-like activity of the proteasome by ixazomib prevents mitochondrial dysfunction ... 
      Sánchez Vergara, Gina; Chalmers, Stefanie; Ahumada, Xavier; Montecinos, Luis; Olmedo Alegría, Ivonne Odette; Eisner, Verónica; Riveros, Ana; Kogan, Marcelo J.; Lavandero González, Sergio; Pedrozo Cibils, Zully; Donoso Laurent, Paulina (Public Library Science, 2020)
      The heart is critically dependent on mitochondrial respiration for energy supply. Ischemia decreases oxygen availability, with catastrophic consequences for cellular energy systems. After a few minutes of ischemia, the ...
    • Intranasal administration of gold nanoparticles designed to target the central nervous system: Fabrication ... 
      Gallardo Toledo, Eduardo; Tapia Arellano, Andreas; Celis, Freddy; Sinai, Tomer; Campos, Marcelo; Kogan, Marcelo J.; Sintov, Amnon C. (Elsevier, 2020)
      The presence of the blood-brain barrier (BBB) limit gold nanoparticles (GNP) accumulation in central nervous system (CNS) after intravenous (IV) administration. The intranasal (IN) route has been suggested as a good strategy ...
    • Label-free oligonucleotide-based SPR biosensor for the detection of the gene mutation causing prothrombin-related ... 
      Sierpe, Rodrigo; Kogan, Marcelo J.; Bollo Dragnic, Soledad (MDPI, 2020)
      Prothrombin-related thrombophilia is a genetic disorder produced by a substitution of a single DNA base pair, replacing guanine with adenine, and is detected mainly by polymerase chain reaction (PCR). A suitable alternative ...
    • Light-induced release of the cardioprotective peptide angiotensin-(1-9) from thermosensitive liposomes with ... 
      Bejarano, Julián; Rojas, Aldo; Ramírez Sagredo, Andrea; Riveros Salvatierra, Ana; Morales Zavala, Francisco; Flores, Yvo; Riquelme Meléndez, Jaime; Guzmán, Fanny; Araya, Eyleen; Chiong Lay, Mario; Ocaranza, María Paz; Morales Montecinos, Javier; Villamizar Sarmiento, María Gabriela; Sánchez Vergara, Gina; Lavandero González, Sergio; Kogan, Marcelo J. (Elsevier, 2020)
      Angiotensin-(1-9), a component of the non-canonical renin-angiotensin system, has a short half-life in blood. This peptide has shown to prevent and/or attenuate hypertension and cardiovascular remodeling. A controlled ...
    • Plasmonic nanoparticles as optical sensing probes for the detection of alzheimer’s disease 
      Oyarzún, María Paz; Tapia Arellano, Andreas; Cabrera, Pablo; Jara Guajardo, Pedro; Kogan, Marcelo J. (MDPI, 2021)
      Alzheimer’s disease (AD), considered a common type of dementia, is mainly characterized by a progressive loss of memory and cognitive functions. Although its cause is multifactorial, it has been associated with the ...
    • Poly-epsilon-caprolactone Nanoparticles Loaded with 4-Nerolidylcatechol (4-NC) for Growth Inhibition of ... 
      Greatti, Vanessa Raquel; Oda, Fernando; Sorrechia, Rodrigo; Kapp, Bárbara Regina; Seraphim, Carolina Manzato; Villas Boas Weckwerth, Ana Carolina; Chorilli, Marlus; Da Silva, Patricia Bento; Eloy, Josimar O.; Kogan, Marcelo J.; Morales Montecinos, Javier; Linhari Rodrigues Pietro, Rosemeire Cristina (MDPI, 2020)
      Dermatophyte fungal infections are difficult to treat because they need long-term treatments. 4-Nerolidylcatechol (4-NC) is a compound found in Piper umbellatum that has been reported to demonstrate significant antifungal ...