Now showing items 1-14 of 14

    • Sagredo, Eduardo A.; Sagredo, Alfredo I.; Blanco, Alejandro; Rojas De Santiago, Pamela; Rivas, Solange; Assar Cuevas, Rodrigo; Pérez, Paola; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo (Elsevier, 2020)
      RNA editing has emerged as a novel mechanism in cancer progression. The double stranded RNA-specific adenosine deaminase (ADAR) modifies the expression of an important proportion of genes involved in cell cycle control, ...
    • Olguín Aguilera, Patricio; Armisen Yáñez, Ricardo; Kukuljan Padilla, Manuel (SOCIEDAD BIOLGIA CHILE, 2006)
      The electrophysiological properties of neurons are determined by the expression of defined complements of ion channels. Nonetheless, the regulation mechanisms of the expression of neuronal ion channels are poorly understood, ...
    • Simon, Felipe; Tapia, Pablo; Armisen Yáñez, Ricardo; Echeverría, César; Gatica, Sebastian; Vallejos, Alejandro; Pacheco Durán, Alejandro; Sanhueza Villanueva, María Eugenia; Alvo Abodovsky, Miriam; Segovia, Erico; Torres, Rubén (Frontiers Media SA, 2017)
      Chronic peritoneal dialysis (PD) therapy is equally efficient as hemodialysis while providing greater patient comfort and mobility. Therefore, PD is the treatment of choice for several types of renal patients. During PD, ...
    • Jain, J.; Moreno, J.; Andaur, R.; Armisen Yáñez, Ricardo; Morales D., Ignacio; Marcelain Cubillos, Katherine; Avaria, G.; Bora, B.; Davis, S.; Pavez, C.; Soto, L. (American Institute of Physics, 2017)
      Plasma focus devices may arise as useful source to perform experiments aimed to study the effects of pulsed radiation on human cells in vitro. In the present work, a table top hundred joules plasma focus device, namely ...
    • Simon, Felipe; Leiva Salcedo, Elías; Armisen Yáñez, Ricardo; Riveros, Ana; Cerda, Oscar; Varela, Diego; Eguiguren, Ana Luisa; Olivero, Pablo; Stutzin Schottlander, Andrés (2010)
      Necrosis is associated with an increase in plasma membrane permeability, cell swelling, and loss of membrane integrity with subsequent release of cytoplasmic constituents. Severe redox imbalance by overproduction of reactive ...
    • Levy, Eric; Marty, Rachel; Gárate Calderón, Valentina; Woo, Brian; Dow, Michelle; Armisen Yáñez, Ricardo; Carter, Hannah; Harismendy, Olivier (Nature, 2016)
      Tumor infiltrating lymphocytes (TILs) have been associated with favorable prognosis in multiple tumor types. The Cancer Genome Atlas (TCGA) represents the largest collection of cancer molecular data, but lacks detailed ...
    • Núñez-Villena, Felipe; Becerra, Alvaro; Echeverría, Cesar; Briceño, Nicolás; Porras Espinoza, Omar; Armisen Yáñez, Ricardo; Varela, Diego; Montorfano, Ignacio; Sarmiento, Daniela; Simon, Felipe (2011)
      Aims: To assess the mechanisms involved in lipopolysaccharide (LPS)-induced neuronal cell death, we examined the cellular consequences of LPS exposure in differentiated PC12 neurons and primary hippocampal neurons. Results: ...
    • Hermosilla, Tamara; Moreno, Cristian; Itfinca, Mircea; Altier, Christophe; Armisen Yáñez, Ricardo; Stutzin Schottlander, Andrés; Zamponi, Gerald W.; Varela, Diego (Taylor and Francis Inc., 2011)
      Angiotensin II regulation of L-type calcium currents in cardiac muscle is controversial and the underlying signaling events are not completely understood. Moreover, the possible role of auxiliary subunit composition of the ...
    • Freire, M.; Lizana, R.; Ramos, L.; Sepúlveda, G.; Blanco, A.; Chernilo, S.; Aren, O.; Fernández, C.; Armisen Yáñez, Ricardo (Elsevier, 2018-04)
    • Torres, Mauricio; Castillo, Karen; Armisen Yáñez, Ricardo; Stutzin Schottlander, Andrés; Soto, Claudio; Hetz Flores, Claudio (2010)
      Prion-related disorders (PrDs) are fatal neurodegenerative disorders characterized by progressive neuronal impairment as well as the accumulation of an abnormally folded and protease resistant form of the cellular prion ...
    • Echeverría, César; Romero, Valentina; Arancibia, Rodrigo; Klahn, Hugo; Montorfano, Ignacio; Armisen Yáñez, Ricardo; Borgna, Vincenzo; Simon, Felipe; Ramírez Tagle, Rodrigo (Springer, 2016)
      Trypanosoma cruzi (T. cruzi) is the parasite that causes Chagas disease. Nifurtimox is the most used drug against the T. cruzi, this drug increases intermediaries nitro group, being mainly responsible for the high toxicity ...
    • Rojas Rivera, Diego; Armisen Yáñez, Ricardo; Colombo, A.; Martínez, G.; Eguiguren, A. L.; Díaz, A.; Kiviluoto, S.; Rodríguez, D.; Patron, M.; Rizzuto, R.; Bultynck, G.; Concha Nordemann, Miguel; Sierralta, J.; Stutzin Schottlander, Andrés; Hetz Flores, Claudio (2012)
      Transmembrane BAX inhibitor motif-containing (TMBIM)-6, also known as BAX-inhibitor 1 (BI-1), is an anti-apoptotic protein that belongs to a putative family of highly conserved and poorly characterized genes. Here we report ...
    • Armisen Yáñez, Ricardo; Marcelain Cubillos, Katherine; Simon, Felipe; Tapia, Julio C.; Toro, Jessica; Quest, Andrew F. G.; Stutzin Schottlander, Andrés (2011)
      Altered expression of some members of the TRP ion channel superfamily has been associated with the development of pathologies like cancer. In particular, TRPM4 levels are reportedly elevated in diffuse large B-cell non-Hodgkin ...
    • Sagredo, A.; Sagredo, Eduardo A.; Cappelli, Claudio; Baez, Pablo; Andaur, Rodrigo E.; Blanco, Constanza; Tapia, Julio C.; Echeverría, César; Cerda, Oscar; Stutzin Schottlander, Andrés; Simon, Felipe; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo (Febs Press Science Publishing by Scientist, 2018)
      Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing ...