Browsing by Author "4899b026-e4f8-44f7-b69c-e3f9fab2b07f"
Now showing items 1-7 of 7
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Carvallo, Pilar; Mateu, Mauricio G.; Sierra, Jose Manuel; Allende, Jorge E. (1988)The protein synthesis initiation factor 2 (eIF2) from Xenopus laevis oocytes has been extensively purified and characterized. Depending upon the purification scheme, eIF2 containing three subunits (α, β and γ) with Mr of ...
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Alvarez, Carolina; Aravena, Andrés; Tapia, Teresa; Rozenblum, Ester; Solís, Luisa; Corvalán, Alejandro; Camus, Mauricio; Acevedo Alvarez, Manuel; Munroe, David; Maass Sepúlveda, Alejandro; Carvallo, Pilar (BioMed Central Ltd., 2016)© 2016 Alvarez et al.Background: Array CGH analysis of breast tumors has contributed to the identification of different genomic profiles in these tumors. Loss of DNA repair by BRCA1 functional deficiency in breast cancer ...
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Espinosa, Claudia; Sjoberg, Marcela; Salazar, Teresa; Rodriguez, Adrian; Cassorla Goluboff, Fernando; Mericq, Verónica; Carvallo, Pilar (Freund Publishing House Ltd, 2008)Mutations in the GH receptor gene have been identified as the cause of growth hormone insensitivity syndrome (GHIS), a rare autosomal recessive disorder. We studied the clinical and biochemical characteristics and the ...
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Carvallo, Pilar; Allende, Jorge E. (1987)The structural specificity of the purified protein synthesis initiation factor 2 (eIF-2) from X. laevis ovary towards analogs of GTP and GDP was studied. The relative affinity of the structural analogs was measured by their ...
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Alvarez, Carolina; Tapia, Teresa; Cornejo, Valeria; Fernandez, Wanda; Muñoz, Alex; Camus, Mauricio; Alvarez, Manuel; Devoto, Luigi; Carvallo, Pilar (2013)Promoter hypermethylation is gaining strength as one of the main mechanisms through which tumor suppressor genes are silenced during tumor progression. Three tumor suppressor genes are frequently found methylated in their ...
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Alvarez, Karin; Hurtado, Claudia; Hevia, Montserrat A.; Wielandt, Ana Maria; De La Fuente, Marjorie; Church, James; Carvallo, Pilar; López Kostner, Francisco (2010)PURPOSE: Lynch syndrome is the most common inherited syndrome of colorectal cancer, caused principally by germline mutations in MLH1 and MSH2. We report our experience with genetic screening in the diagnosis of Lynch ...
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Kohen Skop, Paulina; Castro, Olga; Palomino, Alberto; Muñoz, Alex; Christenson, Lane K.; Sierralta, Walter; Carvallo, Pilar; Strauss, Jerome F.; Devoto, Luigi (2003)This study was designed 1) to assess corpus luteum (CL) steroidogenesis in response to exogenous human chorionic gonadotropin (hCG) at different times during the luteal phase, 2) to examine the effect of hCG on steroidogenic ...