Now showing items 1-15 of 15

    • Oróstica Arévalo, María Lorena; Rosas Chuñil, Carlos; Plaza Parrochia, Francisca; Astorga Leiva, Isis; Gabler Neale, Fernando; García Angulo, Víctor; Romero Osses, Carmen; Vega Blanco, María Margarita (Bentham Science, 2016)
      Background: Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine/metabolic disorder characterized by hyperandrogenemia and in most cases, by hyper-insulinemia in addition to obesity. Besides ovarian dysfunction, ...
    • Oróstica Arévalo, María Lorena; García, Paula; Vera, Carolina; García, Victor; Romero Osses, Carmen; Vega Blanco, María Margarita (Sage, 2018-07)
      Polycystic ovary syndrome (PCOS) affects not only ovarian functions but is also able to affect endometrium metabolism. Around 80% of women with PCOS are obese. High tumor necrosis factor (TNF)- production and low adiponectin ...
    • Oróstica Arévalo, María Lorena; García, Paula; Vera, Carolina; García, Víctor; Romero Osses, Carmen; Vega Blanco, María Margarita (SAGE Publications Inc., 2018)
      © The Author(s) 2017. Polycystic ovary syndrome (PCOS) affects not only ovarian functions but is also able to affect endometrium metabolism. Around 80% of women with PCOS are obese. High tumor necrosis factor (TNF)-α ...
    • Oróstica Arévalo, María Lorena; Lopez, John; Rojas, Israel; Rocco, Jocelyn; Diáz, Patricia; Reuqueń, Patricia; Cardenas, Hugo; Parada Bustamante, Alexis; Orihuela, Pedro A. (BioScientifica Ltd., 2014)
      In the rat oviduct, estradiol (E2) accelerates egg transport by a nongenomic action that requires previous conversion of E2 to methoxyestrogens via catechol-O-methyltranferase (COMT) and activation of estrogen receptor ...
    • Rosas Chuñil, Carlos; Oróstica Arévalo, María Lorena; Poblete, Cristian; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Lavandero González, Sergio; Vega Blanco, María Margarita (SAGE, 2016)
      Background: Women with polycystic ovary syndrome (PCOS) exhibit a low fertility by chronic hyperandrogenemia. Different evidence have shown that androgens could regulate the endoplasmic reticulum (ER) homeostasis and glucose ...
    • Oróstica Arévalo, María Lorena; López, John; Zuñiga, Lidia M.; Utz, Daniella; Díaz, Patricia; Reuquen, Patricia; Parada Bustamante, Alexis; Cardenas, Hugo; Orihuela, Pedro A. (John Wiley and Sons Inc., 2014)
      © 2014 Wiley Periodicals, Inc.Mating shuts down a 2-methoxyestradiol (2ME)-dependent, non-genomic activity that is responsible for accelerating egg transport in the rat oviduct. The aims of this work were to investigate ...
    • Oróstica Arévalo, María Lorena; López, John; Zuñiga, Lidia M.; Utz, Daniella; Díaz, Patricia; Reuquen, Patricia; Parada Bustamante, Alexis; Cardenas, Hugo; Orihuela, Pedro A. (John Wiley and Sons Inc., 2014)
      © 2014 Wiley Periodicals, Inc.Mating shuts down a 2-methoxyestradiol (2ME)-dependent, non-genomic activity that is responsible for accelerating egg transport in the rat oviduct. The aims of this work were to investigate ...
    • Plaza Parrochia, Francisca; Oróstica Arévalo, María Lorena; García, Paula; Vera, Carolina; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (SAGE Publications Inc, 2017)
      Proliferation in endometria of women with polycystic ovarian syndrome (PCOS) is increased, similar to the biosynthesis of androstenediol (estrogenic metabolite). As previously shown, in human endometrial cells, androstenediol ...
    • Oróstica Arévalo, María Lorena (Universidad de Chile, 2016)
      Antecedentes: El síndrome de ovario poliquístico (SOP), patología endocrinometabólica, afecta alrededor del 15% de mujeres en edad fértil, afectando principalmente la función del ovario, aunque también altera la función ...
    • Oróstica Arévalo, María Lorena; Poblete Rivas, Cristian; Romero Osses, Carmen; Vega Blanco, María Margarita (Springer, 2020)
      A pro-inflammatory environment is characteristic of obesity and polycystic ovary syndrome (PCOS). This environment through cytokines secretion negatively affects insulin action. Endometria from women with both conditions ...
    • Oróstica Arévalo, María Lorena; Astorga Leiva, Isis; Plaza Parrochia, Francisca; Vera Castillo, Carolina; García Angulo, Víctor; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Vega Blanco, María Margarita (Springer Nature, 2016)
      BACKGROUND/OBJECTIVES: A high percentage of women having polycystic ovarian syndrome (PCOS) exhibit hyperinsulinemia and obesity. Transforming necrosis factor-alpha (TNF-alpha) is an adipokine that increases in obesity and ...
    • Reuquen, Patricia; Guajardo Correa, Emanuel; Oróstica Arévalo, María Lorena; Curotto, Constanza; Parada Bustamante, Alexis; Cárdenas Villarreal, Hugo; Orihuela, Pedro A. (Institute animal reproduction food research, 2017)
      Vaginocervical stimulation (VCS) induces twice-daily prolactin (PRL) surges resulting in pseudopregnancy in the rat. Furthermore, activation of the extracellular signal-regulated kinase-1/2 (Erk-1/2) is involved in the ...
    • Retamales-Ortega, Rocío; Oróstica Arévalo, María Lorena; Vera, Carolina; Cuevas, Paula; Hernández, Andrea; Hurtado, Iván; Vega Blanco, María Margarita; Romero Osses, Carmen (MDPI AG, 2017)
      © 2017 by the authors. Licensee MDPI, Basel, Switzerland. Ovarian cancer is the eighth most common cancer in women worldwide, and epithelial ovarian cancer (EOC) represents 90% of cases. Nerve growth factor (NGF) and its ...
    • Vera, Carolina Andrea; Oróstica Arévalo, María Lorena; Gabler Neale, Fernando; Ferreira, Arturo; Selman,; Vega Blanco, María Margarita; Romero Osses, Carmen (Spandidos Publications, 2017)
      Ovarian cancer is the seventh most common cancer among women worldwide, causing approximately 120,000 deaths every year. Immunotherapy, designed to boost the body's natural defenses against cancer, appears to be a promising ...
    • Parada Bustamante, Alexis; Oróstica Arévalo, María Lorena; Reuquén, Patricia; Zúñiga, Lidia M.; Cárdenas, Hugo; Orihuela, Pedro A. (Wiley, 2016)
      The oviduct connects the ovary to the uterus, and is subject to changes that influence gamete transport, fertilization, and early embryo development. The ovarian steroids estradiol and progesterone are largely responsible ...