Browsing by Author "4f732b2f-9dfa-43d5-b569-899f5d9d487b"
Now showing items 1-11 of 11
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García Beltrán, Olimpo; Mena, Natalia; Berríos, Tania A.; Castro, Enrique A.; Cassels Niven, Bruce; Núñez González, Marco; Aliaga, Margarita E. (2012)In this Letter we present a new probe, 2-amino-3-hydroxy-2-(hydroxymethyl) propyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (PMR), which can reversibly detect mercuric ions (Hg 2+) in HEPES buffer under physiological ...
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Ortiz, Rocío; Antilén, Mónica; Speisky Cosoy, Hernán; Aliaga, Margarita E.; López Alarcón, Camilo (2011)The analytical parameters of the microplatebased oxygen radicals absorbance capacity (ORAC) method using pyrogallol red (PGR) as probe (ORAC-PGR) are presented. In addition, the antioxidant capacity of commercial beverages, ...
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Ortiz, Rocío; Antilén, Mónica; Speisky Cosoy, Hernán; Aliaga, Margarita E.; López Alarcón, Camilo; Baugh, Steve (AOAC International, 2012)The method was approved by the Expert Review Panel on Strategic Foods Analytical Methods as First Action. See "Standards News," (2012) Inside Laboratory Management, March/April issue. The AOAC Stakeholder Panel on Strategic ...
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Gómez, Marisol; Aliaga, Margarita; Arancibia, Verónica; Moya, Alexis; Segura, Camilo; Nuñez, Marco; Aguirre, Pabla; Nagles, Edgar; García-Beltrán, Olimpo (Royal Society of Chemistry, 2018)A new probe (E)-7-(diethylamino)-3-(3-(thiophen-2-yl)acryloyl)-2H-chromen-2-one (ChC16) was synthesized and studied as a turn-on fluorescent probe, based on a Michael addition mechanism for sensing SO2 derivatives, which ...
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Rojas Romo, Carlos; Aliaga, Margarita E.; Arancibia, Verónica; Gómez, Marisol (Elsevier, 2020)Using the differential pulse anodic stripping voltammetry technique and an in-situ bismuth film deposited on a glassy carbon electrode, a simple and sensitive method for rapid Pb(II) and Cd(II) quantification was developed. ...
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Sandoval Acuña, Cristian; López Alarcón, Camilo; Aliaga, Margarita E.; Speisky Cosoy, Hernán (2012)Mitochondrial dysfunction plays a major role in the development of oxidative stress and cytotoxicity induced by non-steroidal anti-inflammatory drugs (NSAIDs). A major objective of the present study was to investigate ...
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Aliaga, Margarita E.; López Alarcón, Camilo; Barriga, Germán; Olea Azar, Claudio; Speisky Cosoy, Hernán (2010)Prompted by the recently reported capacity of the physiologically occurring Cu(I)-[glutathione]2 complex (Cu(I)-[GSH)]2) to reduce oxygen, the effect of various GSH-binding metals (Co2+, Cd2+, Zn2+, Pb2+, Al3+, Hg2+ and ...
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Aliaga, Margarita E.; López Alarcón, Camilo; García Río, Luis; Martín-Pastor, Manuel; Speisky Cosoy, Hernán (2012)The intracellularly-occurring Cu(I)-glutathione complex (Cu(I)-[GSH] 2) has the ability to reduce molecular oxygen into superoxide. Removal of such radicals leads to the irreversible conversion of Cu(I)-[GSH] 2 into the ...
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Speisky Cosoy, Hernán; López Alarcón, Camilo; Olea Azar, Claudio; Sandoval-Acua, Cristian; Aliaga, Margarita E. (2011)The physiologically occurring copper-glutathione complex, [Cu(I)-[GSH]2], has the ability to react continually with oxygen, generating superoxide anions (O 2 -). We addressed here the effects that superoxide removal has ...
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Aliaga, Margarita; Carrasco Pozo, Catalina; López Alarcón, Camilo; Olea Azar, Claudio; Speisky Cosoy, Hernán (2011)The intracellularly-occurring Cu(I)-glutathione complex (Cu(I)-[GSH](2)) has the ability to reduce molecular oxygen into superoxide radicals (O-2(center dot-)). Based on such ability, we addressed the potential of this ...
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García Beltrán, Olimpo; Mena Jiménez, Natalia; Pérez, Edwin; Cassels Niven, Bruce; Núñez González, Marco; Werlinger, Francisca; Zavala, Daniel; Aliaga, Margarita E.; Pavez, Paulina (Elsevier, 2011)Two fluorescence probes for the detection of cysteine (Cys), glutathione (GSH) and other biothiols, such as homocysteine (Hcy) and cysteinyl-glycine (Cys-Gly), were developed. These molecular probes are coumarin-based ...