Browsing by Author "50ebb476-cef7-46b3-8260-1f8ba31d78c6"

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    • Influence of CYP3A4/5 polymorphisms in the pharmacokinetics of levonorgestrel: A pilot study Influencia de ... 
      Moreno, Iván; Quiñones, Luis; Catalán, Johanna; Miranda, Carla; Roco, Ángela; Sasso, Jaime; Tamayo Carrillo, Evelyn; Cáceres, Dante; Tchernitchin, Andrei N.; Gaete, Leonardo; Saavedra, Iván (2012)
      Introduction. Levonorgestrel a synthetic progestagen used for endometriosis, dysmenorrhea and emergency contraception, is quickly and completely absorbed in the digestive tract. levonorgestrel is predominantly metabolised ...
    • Relative bioavailability study with two oral formulations of topiramate using a validated UPLC-MS/MS method 
      Saavedra Saavedra, Iván; Tamayo Carrillo, Evelyn; Gamboa, A.; Sasso Aguirre, Jaime Alfredo; Varela Figueroa, Nelson; Moreno, Iván; Marchant Lavín, Dafne; Cáceres Lillo, Dante; Quiñones Sepúlveda, Luis (2010)
      Changes in bioavailability of anticonvulsant drugs such as topiramate may cause loss of or worsened seizure control. Thus, the purpose of this study was to evaluate, in a double-blind crossover design, the bioavailability ...