Now showing items 1-3 of 3

    • Ponce, Iván; Aldunate, Carmen; Valenzuela, Lucía; Sepúlveda Contreras, Sofía; Garrido, Gilda; Kemmerling Weis, Ulrike; Cabrera Vallejos, Gonzalo; Galanti Garrone, Norbel (Wiley, 2017)
      FLAP endonucleases (FEN) are involved both in DNA replication and repair by processing DNA intermediaries presenting a nucleotide flap using its phosphodiesterase activity. In spite of these important functions in DNA ...
    • Ormeno, Fernando; Barrientos, Camila; Ramírez, Santiago; Ponce, Iván; Valenzuela, Lucía; Sepúlveda, Sofía; Bitar, Maina; Ulrike Kemmerling, Weis; Machado, Carlos Renato; Cabrera Vallejos, Gonzalo; Galanti Garrone, Norbel (Public Library Science, 2016-06-10)
      Trypanosoma cruzi, the etiological agent of Chagas' disease, presents three cellular forms (trypomastigotes, epimastigotes and amastigotes), all of which are submitted to oxidative species in its hosts. However, T. cruzi ...
    • Valenzuela, Lucía; Sepúlveda, Soía; Ponce, Iván; Galanti Garrone, Norbel; Cabrera, Gonzalo (Wiley-Liss Inc., 2018)
      © 2018 Wiley Periodicals, Inc. Trypanosoma cruzi, the causative agent of Chagas’ disease survives to DNA damage generated by ROS/RNS inside to their different hosts. In recent eukaryotes, oxidative DNA damage is repaired ...