Browsing by Author "5224cd38-f54a-4deb-8f2f-ebbaaac49351"

Now showing items 1-3 of 3

    • An ERcentric view of Parkinson's disease 
      Mercado, Gabriela; Valdés, Pamela; Hetz Flores, Claudio (2013)
      Parkinson's disease (PD) is the second most common neurodegenerative disease and is characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta and the accumulation of intracellular ...
    • Hepcidin inhibits apical iron uptake in intestinal cells 
      Mena, Natalia P.; Esparza, Andrés; Tapia, Victoria; Valdés, Pamela; Núñez González, Marco (2007)
      Hepcidin (Hepc) is considered a key mediator in iron trafficking. Although the mechanism of Hepc action in macrophages is fairly well established, much less is known about its action in intestinal cells, one of the main ...
    • Upregulation of γ-glutamate-cysteine ligase as part of the long-term adaptation process to iron accumulation ... 
      Aguirre, Pabla; Valdés, Pamela; Aracena Parks, Paula; Tapia, Victoria; Núñez González, Marco (2007)
      Reactive iron is an important prooxidant factor, whereas GSH is a crucial component of a long-term adaptive system that allows cells to function during extended periods of high oxidative stress. In this work, the adaptive ...