Browsing by Author "525002ec-0c73-49c7-b62d-18a424994755"

Now showing items 1-20 of 38

    • Accuracy of power mode transcranial Doppler in the diagnosis of brain death 
      Brunser, Alejandro M.; Lavados Germain, Pablo Manuel; Cárcamo, Daniel A.; Hoppe, Arnold; Olavarría, Verónica V.; López, Javiera; Muñoz, Paula; Palacios Rivas, Rodrigo (Elsevier (Singapore) Pte Ltd, 2015)
      © 2014.Background: The diagnosis of brain death (BD) is complex. For this reason, we aimed to evaluate the accuracy of power mode transcranial Doppler (PMD-TCD) in diagnosing BD. Patients and methods: Patients admitted to ...
    • Applicability of ENCHANTED trial results to current acute ischemic stroke patients eligible for intravenous ... 
      Robinson, Thompson G.; Bray, Benjamin D.; Paley, Lizz; Sprigg, Nikola; Wang, Xia; Arima, Hisatomi; Bath, Philip M.; Broderick, Joseph P.; Durham, Alice C.; Kim, Jong S.; Lavados Germain, Pablo Manuel; Lee, Tsong Hai; Martins, Sheila; Nguyen, Thang H.; Pandian, Jeyaraj D.; Parsons, (SAGE Publications Inc., 2019)
      Background: Randomized controlled trials provide high-level evidence, but the necessity to include selected patients may limit the generalisability of their results. Methods: Comparisons were made of baseline and outcome ...
    • Blood pressure variability and outcome in acute ischemic and hemorrhagic stroke: a post hoc analysis of the ... 
      Minhas, Jatinder S.; Wang, Xia; Lavados Germain, Pablo Manuel; Moullaali, Tom J.; Arima, Hisatomi; Billot, Laurent; Hackett, Maree L.; Olavarria, Veronica V.; Middleton, Sandy; Pontes-Neto, Octavio; De Silva, H. Asita; Lee, Tsong Hai; Pandian, Jeyaraj D.; Mead, Gillian E.; Watkins (Nature Publishing Group, 2019)
      The Head Positioning in Acute Stroke Trial (HeadPoST) is a pragmatic, international, cluster crossover randomized trial of 11,093 patients with acute stroke assigned to a lying-flat (0°) or sitting-up (head elevated ≥30°) ...
    • Characteristics, management and response to alteplase in China versus non-China participants of the ENCHANTED trial 
      Song, Lily; Wang, Xia; Robinson, Thompson; Lindley, Richard I.; Arima, Hisatomi; Lavados Germain, Pablo Manuel; Chen, Xiaoying; Chalmers, John; Anderson, Craig S.; Anderson, Craig S. (BMJ Publishing Group, 2017)
      © 2017 BMJ Publishing Group. All rights reserved. Background The characteristics of patients with acute ischaemic stroke (AIS) and their management vary across regions, which may influence outcomes. We examined for ...
    • Characterization of patients with embolic strokes of undetermined source in the navigate esus randomized trial 
      Kasner, Scott E.; Lavados Germain, Pablo Manuel (Elsevier, 2018-06)
      Background: The New Approach Rivaroxaban Inhibition of Factor Xa in a Global Trial vs. ASA to Prevent Embolism in Embolic Stroke of Undetermined Source (NAVIGATE-ESUS) trial is a randomized phase-III trial comparing ...
    • Cluster-randomized, crossover trial of head positioning in acute stroke 
      Anderson, C. S.; Arima, H.; Lavados Germain, Pablo Manuel; Billot, L.; Hackett, M. L.; Olavarría, V. V.; Muñoz Venturelli, Paula; Brunser, A.; Peng, B.; Cui, L.; Song, L.; Rogers, K.; Middleton, S.; Lim, J. Y.; Forshaw, D.; Lightbody, C. E.; Woodward, M.; Pontes‑Neto, O.; Silva, H. A. De; Lin, R. -T; Lee, T.-H; Pandian, J. D.; Mead, G. E.; Robinson, T.; Watkins, C. (Massachusetts Medical Soc, 2017)
      BACKGROUND The role of supine positioning after acute stroke in improving cerebral blood flow and the countervailing risk of aspiration pneumonia have led to variation in head positioning in clinical practice. We wanted ...
    • Development of the Standards of Reporting of Neurological Disorders (STROND) checklist: A guideline for the ... 
      Bennett, Derrick A.; Brayne, Carol; Feigin, Valery L.; Barker-Collo, Suzanne; Brainin, Michael; Davis, Daniel; Gallo, Valentina; Jetté, Nathalie; Karch, André; Kurtzke, John F.; Lavados Germain, Pablo Manuel; Logroscino, Giancarlo; Nagel, Gabriele; Preux, Pierre Marie; Rothwell, Peter M. (Lippincott Williams and Wilkins, 2015)
      © 2015 American Academy of Neurology.Background: Incidence and prevalence studies of neurologic disorders play an important role in assessing the burden of disease and planning services. However, the assessment of disease ...
    • Diffusion-weighted imaging determinants for acute ischemic stroke diagnosis in the emergency room 
      Brunser, Alejandro M.; Cavada Chacón, Gabriel; Muñoz Venturelli, Paula; Olavarría, Verónica; Rojo, Alexis; Almeida, Juan; Díaz, Violeta; Hoppe, Arnold; Lavados Germain, Pablo Manuel (Springer, 2018-07)
      The aim of this study was to investigate the clinical-radiological determinants of diffusion-weighted image (DWI) abnormalities in patients with suspected acute ischemic stroke (AIS) seen at the emergency room (ER). ...
    • Early Blood Pressure Lowering Does Not Reduce Growth of Intraventricular Hemorrhage following Acute ... 
      Chan, Edward; Anderson, Craig S.; Wang, Xia; Arima, Hisatomi; Saxena, Anubhav; Moullaali, Tom J.; Delcourt, Candice; Wu, Guojun; Wang, Jinchao; Chen, Guofang; Lavados Germain, Pablo Manuel; Stapf, Christian; Robinson, Thompson; Chalmers, John (S. Karger AG, 2016)
      © 2016 The Author(s). Background: Intraventricular hemorrhage (IVH) extension is common following acute intracerebral hemorrhage (ICH) and is associated with poor prognosis. Aim: To determine whether intensive blood pressure ...
    • Early blood pressure lowering in patients with intracerebral haemorrhage and prior use of antithrombotic ... 
      Lili, Song; Sandset, Else Charlotte; Arima, Hisatomi; Heeley, Emma; Delcourt, Candice; Chen, Guofeng; Yang, Jie; Wu, Guojun; Wang, Xia; Lavados Germain, Pablo Manuel; Huang, Yining; Stapf, Christian; Wang, Jiguang; Robinson, Thompson; Chalmers, John; Lindley, Richard I.; Anderson, Craig S. (BMJ Publishing Group, 2016-12)
      Objective Antithrombotic agents increase risks of intracerebral haemorrhage (ICH) and associated adverse outcomes. We determined differential effects of early blood pressure (BP) lowering in patients with/without ...
    • Evaluación del minimental abreviado de la evaluación funcional del adulto mayor (EFAM) como screening para ... 
      Jiménez Fernández, Daniel; Lavados Germain, Pablo Manuel; Rojas, Paula; Henríquez, Claudio; Silva, Fernando; Guillón, Marta (Sociedad Médica de Santiago, 2017)
      Background: The usefulness of the abbreviated Mini-Mental State Examination included in the Chilean Functional assessment of elderly people (MMSE- EFAM) to detect Dementia has not been determined. Aim: To assess the ...
    • First-Ever Stroke and Transient Ischemic Attack Incidence and 30-Day Case-Fatality Rates in a Population-Based ... 
      Bahit, Cecilia; Coppola, Mariano L.; Riccio, Patricia M.; Cipriano, Lauren E.; Roth, Gregory A.; Lopes, Renato D.; Feigin, Valery L.; Borrego Guerrero, Brenda; Martino, Maximiliano de; Díaz, Alejandro; Ferrante, Daniel; Funaro, Fernando; Lavados Germain, Pablo Manuel; Laura Lewin, M.; López, Daniel H.; Macarrone, Patricia; Marciello, Rafael; Marino, Diego; Martens, Cecilia; Martínez, Paula; Odriozola, Guillermo; Rabinstein, Alejandro; Saposnik, Gustavo; Silva, Damian; Suasnabar, Ramón; Truelsen, Thomas; Uzcudun, Araceli; Viviani, Carlos A.; Sposato, Luciano A. (Lippincott Williams & Wilkins, 2016)
      Background and Purpose-Epidemiological data about stroke are scarce in low-and middle-income Latin-American countries. We investigated annual incidence of first-ever stroke and transient ischemic attack (TIA) and 30-day ...
    • Frequency, determinants, and effects of early seizures after thrombolysis for acute ischemic stroke The ... 
      Xu, Ying; Hackett, Maree L.; Chalmers, John; Lindley, Richard I.; Wang, Xia; Li, Qiang; Robinson, Thompson; Arima, Hisatomi; Lavados Germain, Pablo Manuel; Anderson, Craig S. (Lippincott Williams & Wilkins, 2017)
      Background: Seizures after ischemic stroke have not been well-studied. We aim to determine the frequency, determinants, and significance of early seizures after thrombolysis for acute ischemic stroke. Methods: Data are ...
    • Head position and cerebral blood flow velocity in acute ischemic stroke: A systematic review and meta-analysis 
      Olavarría, Verónica V.; Arima, Hisatomi; Anderson, Craig S.; Brunser, Alejandro M.; Muñoz-Venturelli, Paula; Heritier, Stephane; Lavados Germain, Pablo Manuel (S. Karger AG, 2014)
      Background: Patients with acute ischemic stroke (AIS) have impaired vasomotor reactivity, especially in the affected cerebral hemisphere, such that they may depend directly on systemic blood pressure to maintain perfusion ...
    • Impact of Low Ankle-Brachial Index on the Risk of Recurrent Vascular Events 
      Abboud, Halim; Monteiro Tavares, Linsay; Labreuche, Julien; Arauz, Antonio; Bryer, Alan; Lavados Germain, Pablo Manuel; Massaro, Ayrton; Munoz Collazos, Mario; Steg, Philippe Gabriel; Yamout, Bassem I.; Vicaut, Eric; Amarenco, Pierre (NLM (Medline), 2019)
      Background and Purpose- Low ankle-brachial index (ABI) identifies a stroke subgroup with high risk of recurrent stroke, cardiovascular events, and death. However, limited data exist on the relationship between low ABI and ...
    • Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke ... 
      Anderson, Craig S.; Huang, Yining; Lindley, Richard I.; Chen, Xiaoying; Arima, Hisatomi; Chen, Guofang; Li, Qiang; Billot, Laurent; Delcourt, Candice; Bath, Philip M.; Broderick, Joseph P.; Demchuk, Andrew M.; Donnan, Geoffrey A.; Durham, Alice C.; Lavados Germain, Pablo Manuel (Lancet Publishing Group, 2019)
      Background: Systolic blood pressure of more than 185 mm Hg is a contraindication to thrombolytic treatment with intravenous alteplase in patients with acute ischaemic stroke, but the target systolic blood pressure for ...
    • Intensive care unit admission for patients in the INTERACT2 ICH blood pressure treatment trial: characteristics, ... 
      Wartenberg, Katja E.; Wang, Xia; Muñoz Venturelli, Paula; Rabinstein, Alejandro A.; Lavados Germain, Pablo Manuel; Anderson, Craig S.; Robinson, Thompson (Springer, 2017-06)
      Background Wide variation exists in criteria for accessing intensive care unit (ICU) facilities for managing patients with critical illnesses such as acute intracerebral hemorrhage (ICH). We aimed to determine the predictors ...
    • Intracerebral hemorrhage location and outcome among INTERACT2 participants 
      Delcourt, Candice; Sato, Shoichiro; Zhang, Shihong; Sandset, Else Charlotte; Zheng, Danni; Chen, Xiaoying; Hackett, Maree L.; Arima, Hisatomi; Hata, Jun; Heeley, Emma; Salman, Rustam Al Shahi; Robinson, Thompson; Davies, Leo; Lavados Germain, Pablo Manuel; Lindley, Richard I.; Stap (Lippincott Williams and Wilkins, 2017)
      © 2017 The Author(s).Objective: To clarify associations between intracerebral hemorrhage (ICH) location and clinical outcomes among participants of the main phase Intensive Blood Pressure Reduction in Acute Cerebral ...
    • Low dose vs standard dose alteplase for patients with acute ischemic stroke secondary analysis of the ... 
      Wang, Xia; Robinson, Thompson G.; Lee, Tsong-Hai; Lavados Germain, Pablo Manuel (American Medical Association, 2017)
      IMPORTANCE: A lower dose of intravenous alteplase appears to be a safer treatment option than the standard dose, reducing the risk of symptomatic intracerebral hemorrhage. There is uncertainty, however, over how this effect ...
    • Low-dose versus standard-dose intravenous alteplase in acute ischemic stroke 
      Anderson, C. S.; Robinson, T.; Lindley, R. I.; Arima, H. H.; Lavados Germain, Pablo Manuel; Lee, T. H.; Broderick, J. P.; Chen, X.; Chen, G.; Sharma, V. K.; Kim, J. S.; Thang, N. H.; Cao, Y.; Parsons, M. W.; Levi, C.; Huang, Y.; Olavarria, V. V.; Demchuk, A. M.; Bath, P. M.; Donnan, G. A.; Martins, S.; Pontes Neto, O. M.; Silva, F.; Ricci, S.; Roffe, C.; Pandian, J.; Billot, L.; Woodward, M.; Li, Q.; Wang, X.; Wang, J.; Chalmers, J. (Massachusetts Medical Soc., 2016)
      BACKGROUND Thrombolytic therapy for acute ischemic stroke with a lower-than-standard dose of intravenous alteplase may improve recovery along with a reduced risk of intracerebral hemorrhage. METHODS Using a 2-by-2 ...