Browsing by Author "54222349-e1d5-4d62-9800-6fa6007b246b"

Now showing items 1-6 of 6

    • Altered Steroid Metabolism and Insulin Signaling in PCOS Endometria: Impact in Tissue Function 
      Oróstica Arévalo, María Lorena; Rosas Chuñil, Carlos; Plaza Parrochia, Francisca; Astorga Leiva, Isis; Gabler Neale, Fernando; García Angulo, Víctor; Romero Osses, Carmen; Vega Blanco, María Margarita (Bentham Science, 2016)
      Background: Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine/metabolic disorder characterized by hyperandrogenemia and in most cases, by hyper-insulinemia in addition to obesity. Besides ovarian dysfunction, ...
    • Effect of estradiol on the expression of angiogenic factors in epithelial ovarian cancer 
      Valladares, Macarena; Plaza Parrochia, Francisca; Lepez, Macarena; López Ponce, Daniela; Gabler Neale, Fernando; Gayan, Patricio; Selman, Alberto; Vega Blanco, María Margarita; Romero Osses, Carmen (Francisco Hernández, Editor, 2017)
      Introduction: Ovarian cancer presents a high angiogenesis (formation of new blood vessels) regulated by pro-angiogenic factors, mainly vascular endothelial growth factor (VEGF) and nerve growth factor (NGF). An association ...
    • Endometrium and steroids, a pathologic overview 
      Plaza Parrochia, Francisca; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (Elsevier, 2017)
      Normal endometrial function requires of cell proliferation and differentiation; therefore, disturbances in these processes could lead to pathological entities such as hyperplasia and endometrial adenocarcinoma, where cell ...
    • Molecular mechanisms of androstenediol in the regulation of the proliferative process of human endometrial cells 
      Plaza Parrochia, Francisca; Oróstica Arévalo, María Lorena; García, Paula; Vera, Carolina; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (SAGE Publications Inc, 2017)
      Proliferation in endometria of women with polycystic ovarian syndrome (PCOS) is increased, similar to the biosynthesis of androstenediol (estrogenic metabolite). As previously shown, in human endometrial cells, androstenediol ...
    • Proinflammatory environment and role of TNF-α in endometrial function of obese women having polycystic ... 
      Oróstica Arévalo, María Lorena; Astorga Leiva, Isis; Plaza Parrochia, Francisca; Vera Castillo, Carolina; García Angulo, Víctor; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Vega Blanco, María Margarita (Springer Nature, 2016)
      BACKGROUND/OBJECTIVES: A high percentage of women having polycystic ovarian syndrome (PCOS) exhibit hyperinsulinemia and obesity. Transforming necrosis factor-alpha (TNF-alpha) is an adipokine that increases in obesity and ...
    • The insulin-sensitizing mechanism of myo-inositol is associated with AMPK activation and GLUT-4 expression ... 
      Cabrera Cruz, Heidy; Oróstica, Lorena; Plaza Parrochia, Francisca; Torres Pinto, Ignacio; Romero, Carmen; Vega, Margarita (American Physiological Society, 2020)
      Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder characterized by hyperandrogenism and ovulatory dysfunction but also obesity and hyperinsulinemia. These characteristics induce an insulin-resistant state ...