Browsing by Author "543b3789-709d-4826-863f-2ec304b1fa4b"

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    • Neonicotinic analogues: Selective antagonists for α4β2 nicotinic acetylcholine receptors 
      Faundez Parraguez, Manuel; Farías Rabelo, Nicolás; González Gutiérrez, Juan Pablo; Etcheverry Berríos, Alvaro; Alzate-Morales, Jans; Adasme-Carreño, Francisco; Varas, Rodrigo; Bermudez, Isabel; Iturriaga-Vásquez, Patricio (2013)
      Nicotine is an agonist of nicotinic acetylcholine receptors (nAChRs) that has been extensively used as a template for the synthesis of α4β2-preferring nAChRs. Here, we used the N-methyl-pyrrolidine moiety of nicotine to ...