Browsing by Author "57531202-c479-4254-9385-51a62f4cc51f"

Now showing items 1-2 of 2

    • Development of a new promoter to avoid the silencing of genes in the production of recombinant antibodies ... 
      Zúñiga, Roberto A.; Gutiérrez-González, Matías; Collazo, Norberto; Sotelo, Pablo Hérnan; Ribeiro, Carolina H.; Altamirano, Claudia; Lorenzo, Carmen; Aguillón, Juan Carlos; Molina, María Carmen (BioMed Central Ltd., 2019)
      Background: The production of recombinant proteins in mammalian cell lines is one of the most important areas in biopharmaceutical industry. Viral transcriptional promoters are widely used to express recombinant proteins ...
    • Transcription factor engineering in CHO cells for recombinant protein production 
      Gutiérrez-González, Matías; Latorre, Yesenia; Zúñiga, Roberto; Aguillón, Juan Carlos; Molina, María Carmen; Altamirano, Claudia (Taylor and Francis Ltd, 2019)
      The continuous increase of approved biopharmaceutical products drives the development of more efficient recombinant protein expression systems. Chinese hamster ovary (CHO) cells are the mainstay for this purpose but have ...