Now showing items 1-16 of 16

    • Guzmán, Leda; Depix, María S.; Salinas, Ana M.; Roldán, Rosa; Aguayo, Francisco; Silva, Alejandra; Vinet, Raul (2012)
      Background: Chronic obstructive pulmonary disease (COPD) is a disorder associated to cigarette smoke and lung cancer (LC). Since epigenetic changes in oncogenes and tumor suppressor genes (TSGs) are clearly important in ...
    • Calaf, Gloria M.; Aguayo, Francisco; Sergi, Consolato M.; Juarranz, Angeles; Roy, Debasish (HINDAWI, 2018)
    • Silva-Pavez, Eduardo; Villar, Paulina; Trigo, César; Caamaño, Esteban; Niechi, Ignacio; Pérez, Pablo; Muñoz, Juan P.; Aguayo, Francisco; Burzio, Verónica A.; Varas Godoy, Manuel; Castro, Ariel F.; Colombo, María I.; Tapia, Julio C. (Nature Publishing Group, 2019)
      Protein kinase CK2 is a highly conserved and constitutively active Ser/Thr-kinase that phosphorylates a large number of substrates, resulting in increased cell proliferation and survival. A known target of CK2 is Akt, a ...
    • Núñez Acurio, Daniela; Bravo Rodríguez, Denisse; Aguayo, Francisco (MDPI, 2020)
      Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer. Its development has been associated with diverse factors such as tobacco smoking and alcohol consumption. In addition, it has been suggested that ...
    • Muñoz, Juan Pablo; González, Carolina; Parra, Bárbara; Corvalán, Alejandro H.; Tornesello, Maria Lina; Eizuru, Yoshito; Aguayo, Francisco (2012)
      The smoking habit is the most important, but not a sufficient cause for lung cancer development. Several studies have reported the human papillomavirus type 16 (HPV16) presence and E6 and E7 transcripts expression in lung ...
    • Cabeça, Tatiane Karen; Abreu, Alice de Mello; Andrette, Rafael; Lino, Vanesca de Souza; Morale, Mirian Galliote; Aguayo, Francisco; Termini, Lara; Villa, Luisa Lina; Lepique, Ana Paula; Boccardo, Enrique (MDPI AG, 2019)
      © 2019 by the authors. Licensee MDPI, Basel, Switzerland.Persistent infection with high-risk human papilloma virus (HR-HPV) is the main risk factor for the development of invasive cervical cancer although is not sufficient ...
    • Aguayo, Francisco; Khan, Noureen; Koriyama, Chihaya; González, Carolina; Ampuero Llanos, Sandra; Padilla, Oslando; Solís, Luisa; Eizuru, Yoshito; Corvalán, Alejandro; Akiba, Suminori (2011)
      Background: Human papillomavirus (HPV) and Epstein Barr virus (EBV) have been found in breast carcinomas (BCs) around the world. In this study, fifty-five BCs from Chile were analyzed for HPV and EBV presence. In addition, ...
    • Aguayo, Francisco; Anwar, Muhammad; Koriyama, Chihaya; Castillo, Andres; Sun, Quanfu; Morewaya, Jacob; Eizuru, Yoshito; Akiba, Suminori (2010)
      Background. Although human papillomavirus (HPV) genome has been detected in lung cancer, its prevalence is highly variable around the world. Higher frequencies have been reported in far-east Asian countries, when compared ...
    • Calaf, Gloria M.; Bleak, Tammy C.; Muñoz, Juan P.; Aguayo, Francisco (Spandidos, 2020)
      Breast cancer is a major health problem and accounted for 11.6% of all new cancer cases and 6.6% of all cancer deaths among women worldwide in 2018. However, its etiology has remained elusive. According to epidemiological ...
    • Gheit, Tarik; Muñoz, Juan Pablo; Levican, Jorge; González, Carolina; Ampuero Llanos, Sandra; Parra, Bárbara; Gaggero Brillouet, Aldo; Corvalán, Alejandro H.; Uribe Meneses, Manuel Ángel; Tommasino, Massimo; Aguayo, Francisco (2012)
      Lung cancer is a leading pathology strongly associated with the smoking habit. However, a viral etiology for a subset of patients developing lung cancer has been suggested. Polyomaviruses (PyVs) are small double stranded ...
    • Calaf, Gloria M.; Urzúa Tobar, Ulises; Termini, Lara; Aguayo, Francisco (Impact Journals LLC, 2018)
      © Calaf et al. Breast, cervical and ovarian cancers are highly prevalent in women worldwide. Environmental, hormonal and viral-related factors are especially relevant in the development of these tumors. These factors are ...
    • Bernal, Carolina; Aguayo, Francisco; Villarroel, Cynthia; Vargas, Macarena; Díaz, Ignacio; Ossandon, Francisco J.; Santibáñez, Eudocia; Palma, Mariana; Aravena, Edmundo; Barrientos, Carlos; Corvalan, Alejandro (2008)
      Purpose: Gastric cancer is a curable disease if diagnosed at early stage. However, most cases are diagnosed at advanced stage because of the lack of screening programs. Therefore, the identification of plasma biomarkers ...
    • Levicán-Asenjo, Jorge; Soto Rifo, Ricardo; Aguayo, Francisco; Gaggero Brillouet, Aldo; Leon, Oscar (Blackwell Publishing Ltd, 2019)
      We have previously shown that infectious pancreatic necrosis virus (IPNV) enters the embryo cell line CHSE-214 by macropinocytosis. In this study, we have extended our investigation into SHK-1 cells, a macrophage-like cell ...
    • Corvalán, Alejandro H.; Ruedlinger, Jenny; de Mayo, Tomas; Polakovicova, Iva; González Hormazábal, Patricio; Aguayo, Francisco (MDPI AG, 2019)
      Epstein-Barr virus (EBV) is an etiological agent for gastric cancer with significant worldwide variations. Molecular characterizations of EBV have shown phylogeographical variations among healthy populations and in ...
    • Prati, Bruna; da Silva Abjaude, Walason; Termini, Lara; Morale, Mirian; Herbster, Suellen; Longatto-Filho, Adhemar; Lima Nunes, Rafaella Almeida; Córdoba Camacho, Lizeth Carolina; Rabelo-Santos, Silvia Helena; Zeferino, Luiz Carlos; Aguayo, Francisco; Boccardo, Enri (Nature, 2019)
      Alterations in specific DNA damage repair mechanisms in the presence of human papillomavirus (HPV) infection have been described in different experimental models. However, the global effect of HPV on the expression of genes ...
    • Rodríguez, Hector; Levican, Jorge; Muñoz, Juan P.; Carrillo, Diego; Acevedo, Mónica L.; Gaggero Brillouet, Aldo; León, Oscar; Gheit, Tarik; Espinoza Navarro, Omar; Castillo, Jorge; Gallegos, Iván; Tommasino, Massimo; Aguayo, Francisco (BioMed Central Ltd., 2015)
      © 2015 Rodríguez et al.Background: A few viruses have been detected in prostate cancer, however their role in the development of this malignancy has not been determined. The aim of this study was to analyze the presence ...