Browsing by Author "6204332b-6718-4349-b992-e52a5e29062b"

Now showing items 1-5 of 5

    • Chitosan-based delivery of avian reovirus fusogenic protein p10 gene: in vitro and in vivo studies towards ... 
      Robles Planells, Claudia; Barrera Ávalos, Carlos; Rojo, Leonel E.; Spencer, Eugenio; Cortez San Martín, Eugenio; Matiacevich, Silvia; Pavez, Jorge; Milla, Luis A.; Navarro, Franco D.; Martínez, Brandon A; Bravo, Francisco J.; Mella, Andrea; Huidobro Toro, Juan Pablo; Fernández, Ricardo; Escobar Álvarez, Alejandro; Acuña Castillo, Claudio (Hindawi, 2020)
      Reovirus is known to have an anticancer effect in both the preclinical and clinical assays. Current evidence suggests that the reovirus-mediated impact on tumor growth depends on the activation of specific antitumor immune ...
    • Chitosan-based nanoparticles for Intracellular delivery of ISAV fusion protein cDNA into melanoma cells: a ... 
      Robles Planells, Claudia; Sánchez-Guerrero, Giselle; Barrera Ávalos, Carlos; Matiacevich, Silvia; Rojo, Leonel E.; Pavéz, Jorge; Salas Huenuleo, Edison; Kogan, Marcelo J.; Escobar Álvarez, Alejandro; Milla, Luis A.; Fernández, Ricardo; Imarai, Mónica; Spencer, Eugenio; Huidobro Toro, Juan Pablo; Acuña Castillo, Claudio (Hindawi, 2020)
      Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation ...
    • Dead tumor cells expressing infectious salmon anemia virus fusogenic protein favor antigen cross-priming in vitro 
      Morales, Jonathan; Barrera Avalos, Carlos; Castro, Carlos; Castillo, Stephanie; Barrientos, Claudio; Robles Planells, Claudia; López, Ximena; Torres, Ernesto; Montoya, Margarita; Cortez San Martin, Marcelo; Riquelme, Denise; Escobar Álvarez, Alejandro; Fernández, Ricardo; Imarai, Mónica; Sauma Mahaluf, Daniela; Rojo, Leonel E.; Leiva Salcedo, Elias; Acuña Castillo, Claudio (Frontiers media SA, 2017)
      Antigen cross-presentation is a crucial step in the assembly of an antitumor immune response leading to activation of naive CD8 T cells. This process has been extensively used in clinical trials, in which dendritic cells ...
    • Endotoxin-induced vascular endothelial cell migration is dependent on TLR4/NF-κB pathway, NAD(P)H oxidase ... 
      Sarmiento, Daniela; Montorfano, Ignacio; Cáceres, Mónica; Echeverría, César; Fernández, Ricardo; Cabello-Verrugio, Claudio; Cerda, Oscar; Tapia, Pablo; Simon, Felipe (Elsevier Ltd, 2014)
      Endothelial dysfunction is decisive and leads to the development of several inflammatory diseases. Endotoxemia-derived sepsis syndrome exhibits a broad inflammation-induced endothelial dysfunction. We reported previously ...
    • Lipopolysaccharide inhibits the channel activity of the P2X7 receptor 
      Leiva Salcedo, Elías; Coddou, Claudio; Rodríguez, Felipe; Penna, Antonello; López, Ximena; Neira, Tanya; Fernández, Ricardo; Imarai, Mónica; Rios, Miguel; Escobar, Jorge; Montoya, Margarita; Huidobro Toro, Juan; Escobar, Alejandro; Acuña Castillo, Claudio (2011)
      The purinergic P2X7 receptor (P2X7R) plays an important role during the immune response, participating in several events such as cytokine release, apoptosis, and necrosis. The bacterial endotoxin lipopolysaccharide (LPS) ...