Now showing items 1-3 of 3

    • Riquelme, Jaime; Takov, Kaloyan; Santiago Fernández, Concepción; Rossello, Xavier; Lavandero González, Sergio; Yellon, Derek M.; Davidson, Sean M. (Wiley, 2020)
      Small extracellular vesicles (EVs) are novel players in vascular biology. However, a thorough understanding of their production and function remains elusive. Endothelial senescence is a key feature of vascular ageing and ...
    • Rossello, Xavier; Riquelme, Jaime A.; Davidson, Sean M.; Yellon, Derek M. (Wiley, 2018)
      The Reperfusion Injury Salvage Kinase (RISK) pathway is considered the main pro-survival kinase cascade mediating the ischaemic preconditioning (IPC) cardioprotective effect. To assess the role of PI3K-Akt, its negative ...
    • Rossello, Xavier; Riquelme, Jaime A.; He, Zhenhe; Taferner, Stasa; Vanhaesebroeck, Bart; Davidson, Sean M.; Yellon, Derek M. (Springer, 2017)
      Ischemic preconditioning (IPC) limits myocardial infarct size through the activation of the PI3K-Akt signal cascade; however, little is known about the roles of individual PI3K isoforms in cardioprotection. We aimed, ...