Browsing by Author "6353ec4f-4439-449f-b382-22e79ab40a3b"

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    • Antiangiogenic and antitumor effects of trypanosoma cruzi Calreticulin 
      López, Nandy C.; Valck, Carolina; Ramírez, Galia; Rodríguez, Margarita; Ribeiro, Carolina; Orellana, Juana; Maldonado, Ismael; Albini, Adriana; Anacona, Daniel; Lemus, David; Aguilar, Lorena; Schwaeble, Wilhelm; Ferreira, Arturo (2010)
      Background: In Latin America, 18 million people are infected with Trypanosoma cruzi, the agent of Chagas' disease, with the greatest economic burden. Vertebrate calreticulins (CRT) are multifunctional, intra- and extracellular ...
    • Comparative in vivo antiangiogenic effects of calreticulin from Trypanosoma cruzi and Homo sapiens sapiens 
      Toledo, Víctor; Ramírez, Galia; Valck, Carolina; López, Nandy; Ribeiro, Carolina H.; Maldonado, Ismael; Aguilar, Lorena; Lemus, David; Ferreira, Arturo (Society of Biology of Chile, 2010)
      Angiogenesis is a complex multi-step process of neovascularization arising from preexisting blood vessels whose generation is regulated by pro- and anti-angiogenic factors. Both Trypanosoma cruzi calreticulin (TcCRT) and ...
    • F(ab')2 antibody fragments against Trypanosoma cruzi calreticulin inhibit its interaction with the first ... 
      Aguilar, Lorena; Ramírez, Galia; Valck, Carolina; Molina, María C.; Rojas, Álvaro; Schwaeble, Wilhelm; Ferreira, Viviana; Ferreira, Arturo (Society of Biology of Chile, 2005)
      Trypanosoma cruzi calreticulin (TcCRT), described in our laboratory, retains several important functional features from its vertebrate homologues. We have shown that recombinant TcCRT inhibits the human complement system ...
    • Roles of Trypanosoma cruzi calreticulin in parasite-host interactions and in tumor growth 
      Ramírez, Galia; Valck Calderón, Carolina Eliana; Aguilar, Lorena; Kemmerling Weis, Ulrike; López Muñoz, Rodrigo; Navarro Cabrera, Gonzalo; Morello Casté, Antonio; Ferreira, Jorge; Maya Arango, Juan; Galanti Garrone, Norbel; Ferreira, Arturo (2012)
      In Latin America, there are about 10-12 million people infected with Trypanosoma cruzi, the agent of Chagas' disease, one of the most important neglected tropical parasitism. Identification of molecular targets, specific ...