Browsing by Author "686bcd5b-4b9f-4621-9b7c-4770f19c15e1"
Now showing items 1-8 of 8
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López, Nandy C.; Valck, Carolina; Ramírez, Galia; Rodríguez, Margarita; Ribeiro, Carolina; Orellana, Juana; Maldonado, Ismael; Albini, Adriana; Anacona, Daniel; Lemus, David; Aguilar, Lorena; Schwaeble, Wilhelm; Ferreira, Arturo (2010)Background: In Latin America, 18 million people are infected with Trypanosoma cruzi, the agent of Chagas' disease, with the greatest economic burden. Vertebrate calreticulins (CRT) are multifunctional, intra- and extracellular ...
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Roa Henríquez, Ignacio; Moraga, José; Cantín, Mario; Rosas, Carlos; Lemus, David (Universidad de la Frontera, 2015)© 2015, Universidad de la Frontera. All rights reserved.Metastasis is the propagation process of a cancerous focus to an organ other than that in which it started; usually occurring through blood or lymphatic route. The ...
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Garrido, Osvaldo; Letelier, René; Rosas, Carlos; Fuenzalida, Marcela; Ferreira, Arturo; Lemus, David (Society of Biology of Chile, 2010)Tumor resistance to traditional cancer treatments poses an important challenge to modern science. Thus, angiogenesis inhibition is an important emerging cancer treatment. Many drugs are tested and corticosteroids have shown ...
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Roa, Ignacio; Cantín, Mario; Muñoz, Mariela; Rosas, Carlos; Lemus, David (Universidad de la Frontera, 2016)© 2016, Universidad de la Frontera. All rights reserved.Angiogenesis and metastasis are critical events on the tumor invasion process. Their close association is related as a good target in antitumor therapy. The aimwas ...
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Toledo, Víctor; Ramírez, Galia; Valck, Carolina; López, Nandy; Ribeiro, Carolina H.; Maldonado, Ismael; Aguilar, Lorena; Lemus, David; Ferreira, Arturo (Society of Biology of Chile, 2010)Angiogenesis is a complex multi-step process of neovascularization arising from preexisting blood vessels whose generation is regulated by pro- and anti-angiogenic factors. Both Trypanosoma cruzi calreticulin (TcCRT) and ...
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Illanes, Julio; Dabancens, Alfredo; Acuña, Olga; Fuenzalida, Marcela; Guerrero, Anibal; Lopez, Claudia; Lemus, David (Society of Biology of Chile, 2002)In this study, we showed the effect of the betamethasone, sulindac and quinacrine alone or combined, on the inflammatory angiogenesis promoted by polyurethane sponge on mice. The main finding reported here is that the ...
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Fernández, Jaime G.; Rodríguez, Diego A.; Valenzuela, Manuel; Calderon, Claudia; Urzúa, Ulises; Munroe, David; Rosas, Carlos; Lemus, David; Díaz, Natalia; Wright, Mathew C.; Leyton Campos, Lisette; Tapia, Julio C.; Quest, Andrew F. G. (BioMed Central Ltd., 2014)© 2014 Fernández et al.; licensee BioMed Central Ltd.Early in cancer development, tumour cells express vascular endothelial growth factor (VEGF), a secreted molecule that is important in all stages of angiogenesis, an ...
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Sepúlveda, Francisco; Saavedra, Eduardo; Sánchez, Rodrigo; Córdova, Sebastián; Lemus, David; Fuenzalida, Marcela; Vergara, Marcela; Rosas C., Carlos (Universidad de la Frontera, 2019)The VEGF levels and its binding to its receptors are key stages in the regulation of angiogenesis. Acetylsalicylic acid (ASA), widely used in post-myocardial infarction treatment, has been shown to have an anti-angiogenic ...