Now showing items 1-20 of 33

    • Robinson, Thompson G.; Bray, Benjamin D.; Paley, Lizz; Sprigg, Nikola; Wang, Xia; Arima, Hisatomi; Bath, Philip M.; Broderick, Joseph P.; Durham, Alice C.; Kim, Jong S.; Lavados Germain, Pablo Manuel; Lee, Tsong Hai; Martins, Sheila; Nguyen, Thang H.; Pandian, Jeyaraj D.; Parsons, (SAGE Publications Inc., 2019)
      Background: Randomized controlled trials provide high-level evidence, but the necessity to include selected patients may limit the generalisability of their results. Methods: Comparisons were made of baseline and outcome ...
    • Minhas, Jatinder S.; Wang, Xia; Lavados Germain, Pablo Manuel; Moullaali, Tom J.; Arima, Hisatomi; Billot, Laurent; Hackett, Maree L.; Olavarria, Veronica V.; Middleton, Sandy; Pontes-Neto, Octavio; De Silva, H. Asita; Lee, Tsong Hai; Pandian, Jeyaraj D.; Mead, Gillian E.; Watkins (Nature Publishing Group, 2019)
      The Head Positioning in Acute Stroke Trial (HeadPoST) is a pragmatic, international, cluster crossover randomized trial of 11,093 patients with acute stroke assigned to a lying-flat (0°) or sitting-up (head elevated ≥30°) ...
    • Song, Lily; Wang, Xia; Robinson, Thompson; Lindley, Richard I.; Arima, Hisatomi; Lavados Germain, Pablo Manuel; Chen, Xiaoying; Chalmers, John; Anderson, Craig S.; Anderson, Craig S. (BMJ Publishing Group, 2017)
      © 2017 BMJ Publishing Group. All rights reserved. Background The characteristics of patients with acute ischaemic stroke (AIS) and their management vary across regions, which may influence outcomes. We examined for ...
    • Wang, Xia; Arima, Hisatomi; Al-Shahi Salman, Rustam; Woodward, Mark; Heeley, Emma; Stapf, Christian; Lavados Germain, Pablo Manuel; Robinson, Thompson; Huang, Yining; Wang, Jiguang; Delcourt, Candice; Anderson, Craig S. (Lippincott Williams and Wilkins, 2015)
      © 2015 American Heart Association, Inc. BACKGROUND AND PURPOSE - : We developed and validated a simple algorithm to predict the risk of hematoma growth in acute spontaneous intracerebral hemorrhage (ICH) to better inform ...
    • Wang, Xia; Arima, Hisatomi; Al-Shahi Salman, Rustam; Woodward, Mark; Heeley, Emma; Stapf, Christian; Lavados Germain, Pablo Manuel; Robinson, Thompson; Huang, Yining; Wang, Jiguang; Delcourt, Candice; Anderson, Craig S. (Lippincott Williams and Wilkins, 2015)
      © 2015 American Heart Association, Inc. BACKGROUND AND PURPOSE - : We developed and validated a simple algorithm to predict the risk of hematoma growth in acute spontaneous intracerebral hemorrhage (ICH) to better inform ...
    • Ouyang, Menglu; Boaden, Elizabeth; Arima, Hisatomi; Lavados, Pablo M.; Billot, Laurent; Hackett, Maree L.; Olavarria, Veronica V.; Muñoz Venturelli, Paula; Song, Lili; Rogers, Kris; Middleton, Sandy; Pontes Neto, Octavio M.; Lee, Tsong-Hai; Watkins, Caroline; Robinson, Thompson; Anderson, Craig S. (SAGE, 2020)
      Background Dysphagia is associated with aspiration pneumonia after stroke. Data are limited on the influences of dysphagia screen and assessment in clinical practice. Aims To determine associations between a "brief" ...
    • Ouyang, Menglu; Boaden, Elizabeth; Arima, Hisatomi; Lavados Germain, Pablo Manuel; Billot, Laurent; Hackett, Maree L.; Olavarría, Verónica V.; Muñoz Venturelli, Paula; Song, Lili; Rogers, Kris; Middleton, Sandy; Pontes Neto, Octavio M.; Lee, Tsong Hai; Watkins, Caroline; Robinson, Thompson; Anderson, Craig S. (SAGE, 2019)
      Background: Dysphagia is associated with aspiration pneumonia after stroke. Data are limited on the influences of dysphagia screen and assessment in clinical practice. Aims: To determine associations between a “brief” ...
    • Chan, Edward; Anderson, Craig S.; Wang, Xia; Arima, Hisatomi; Saxena, Anubhav; Moullaali, Tom J.; Delcourt, Candice; Wu, Guojun; Wang, Jinchao; Chen, Guofang; Lavados Germain, Pablo Manuel; Stapf, Christian; Robinson, Thompson; Chalmers, John (S. Karger AG, 2016)
      © 2016 The Author(s). Background: Intraventricular hemorrhage (IVH) extension is common following acute intracerebral hemorrhage (ICH) and is associated with poor prognosis. Aim: To determine whether intensive blood pressure ...
    • Lili, Song; Sandset, Else Charlotte; Arima, Hisatomi; Heeley, Emma; Delcourt, Candice; Chen, Guofeng; Yang, Jie; Wu, Guojun; Wang, Xia; Lavados Germain, Pablo Manuel; Huang, Yining; Stapf, Christian; Wang, Jiguang; Robinson, Thompson; Chalmers, John; Lindley, Richard I.; Anderson, Craig S. (BMJ Publishing Group, 2016-12)
      Objective Antithrombotic agents increase risks of intracerebral haemorrhage (ICH) and associated adverse outcomes. We determined differential effects of early blood pressure (BP) lowering in patients with/without ...
    • Chen, Xiaoying; Wang, Xia; Delcourt, Candice; Li, Jingwei; Arima, Hisatomi; Hackett, Maree L.; Robinson, L.; Lavados, Pablo M.; Lindley, Richard I.; Chalmers, John; Anderson, Craig S. (Lippincott Williams & Wilkins, 2020)
      Background and Purpose-Patient-centered outcomes are important. We aimed to determine predictors of health-related quality of life (HRQoL) and develop utility-weighted modified Rankin Scale (mRS) scores in thrombolyzed ...
    • Olavarría, Verónica V.; Lavados Germain, Pablo Manuel; Muñoz Venturelli, Paula; González, Francisca; Gaete, Javier; Martins, Sheila; Arima, Hisatomi; Anderson, Craig S.; Brunser, Alejandro M. (SAGE Publications Inc., 2018)
      © 2017 World Stroke Organization. Background: Whether lying-flat improves blood flow in patients with acute ischemic stroke is unknown. Our aim was to investigate if lying-flat “changes” cerebral blood flow velocities ...
    • Olavarria, Veronica V.; Lavados Germain, Pablo Manuel; Munoz Venturelli, Paula; González, Francisca; Gaete, Javier; Martins, Sheila; Arima, Hisatomi; Anderson, Craig S.; Brunser, Alejandro M. (Sage Publications, 2018-08)
      Background Whether lying-flat improves blood flow in patients with acute ischemic stroke is unknown. Our aim was to investigate if lying-flat changes cerebral blood flow velocities assessed by transcranial Doppler in acute ...
    • Xu, Ying; Hackett, Maree L.; Chalmers, John; Lindley, Richard I.; Wang, Xia; Li, Qiang; Robinson, Thompson; Arima, Hisatomi; Lavados Germain, Pablo Manuel; Anderson, Craig S. (Lippincott Williams & Wilkins, 2017)
      Background: Seizures after ischemic stroke have not been well-studied. We aim to determine the frequency, determinants, and significance of early seizures after thrombolysis for acute ischemic stroke. Methods: Data are ...
    • Olavarría, Verónica V.; Arima, Hisatomi; Anderson, Craig S.; Brunser, Alejandro M.; Muñoz-Venturelli, Paula; Heritier, Stephane; Lavados Germain, Pablo Manuel (S. Karger AG, 2014)
      Background: Patients with acute ischemic stroke (AIS) have impaired vasomotor reactivity, especially in the affected cerebral hemisphere, such that they may depend directly on systemic blood pressure to maintain perfusion ...
    • Anderson, Craig S.; Huang, Yining; Lindley, Richard I.; Chen, Xiaoying; Arima, Hisatomi; Chen, Guofang; Li, Qiang; Billot, Laurent; Delcourt, Candice; Bath, Philip M.; Broderick, Joseph P.; Demchuk, Andrew M.; Donnan, Geoffrey A.; Durham, Alice C.; Lavados Germain, Pablo Manuel (Lancet Publishing Group, 2019)
      Background: Systolic blood pressure of more than 185 mm Hg is a contraindication to thrombolytic treatment with intravenous alteplase in patients with acute ischaemic stroke, but the target systolic blood pressure for ...
    • Delcourt, Candice; Sato, Shoichiro; Zhang, Shihong; Sandset, Else Charlotte; Zheng, Danni; Chen, Xiaoying; Hackett, Maree L.; Arima, Hisatomi; Hata, Jun; Heeley, Emma; Salman, Rustam Al Shahi; Robinson, Thompson; Davies, Leo; Lavados Germain, Pablo Manuel; Lindley, Richard I.; Stap (Lippincott Williams and Wilkins, 2017)
      © 2017 The Author(s).Objective: To clarify associations between intracerebral hemorrhage (ICH) location and clinical outcomes among participants of the main phase Intensive Blood Pressure Reduction in Acute Cerebral ...
    • Minhas, Jatinder S.; Wang, Xia; Arima, Hisatomi; Bath, Philip M.; Billot, Laurent; Broderick, Joseph P.; Donnan, Geoffrey A.; Kim, Jong S.; Lavados Germain, Pablo Manuel; Lee, Tsong Hai; Martins, Sheila Cristina Ouriques; Olavarría, Verónica V.; Pandian, Jeyaraj D.; Pontes-Neto, (S. Karger AG, 2018)
      © 2018 S. Karger AG, Basel. Copyright: All rights reserved. Background: Debate exists as to whether statin pretreatment confers an increased risk of 90-day mortality and symptomatic intracranial haemorrhage (sICH) in acute ...
    • Minhas, Jatinder S.; Wang, Xia; Arima, Hisatomi; Bath, Philip M.; Billot, Laurent; Broderick, Joseph P.; Donnan, Geoffrey A.; Kim, Jong S.; Lavados Germain, Pablo Manuel; Lee, Tsong-Hai; Martins, Sheila Cristina Ouriques; Olavarría, Verónica V.; Pandian, Jeyaraj D.; Pontes Neto, Octavio Marques; Ricci, Stefano; Sato, Shoichiro; Sharma, Vijay K.; Thang, Nguyen H.; Wang, Ji-Guang; Woodward, Mark; Chalmers, John; Anderson, Craig S.; Robinson, Thompson G. (Karger, 2018)
      Background: Debate exists as to whether statin pretreatment confers an increased risk of 90-day mortality and symptomatic intracranial haemorrhage (sICH) in acute ischaemic stroke (AIS) patients treated with intravenous ...
    • Robinson, Thompson G.; Wang, Xia; Arima, Hisatomi; Bath, Philip M.; Billot, Laurent; Broderick, Joseph P.; Demchuk, Andrew M.; Donnan, Geoffery A.; Kim, Jong S.; Lavados Germain, Pablo Manuel; Lee, Tsong Hai; Lindley, Richard I.; Martins, Sheila C.O.; Olavarria, Veronica V.; Pandi (Lippincott Williams and Wilkins, 2017)
      © 2017 American Heart Association, Inc. Background and Purpose'Many patients receiving thrombolysis for acute ischemic stroke are on prior antiplatelet therapy (APT), which may increase symptomatic intracerebral hemorrhage ...
    • Robinson, Thompson G.; Wang, Xia; Arima, Hisatomi; Bath, Philip M.; Billot, Laurent; Broderick, Joseph P.; Demchuk, Andrew M.; Donnan, Geoffery A.; Kim, Jong S.; Lavados Germain, Pablo Manuel; Lee, Tsong Hai; Lindley, Richard I.; Martins, Sheila C. O.; Olavarria, Veronica V.; Pandian, Jeyaraj D.; Parsons, Mark W.; Pontes Neto, Octavio M.; Ricci, Stefano; Sato, Shoichiro; Sharma, Vijay K.; Nguyen, Thang H.; Wang, Ji Guang; Woodward, Mark; Chalmers, John; Anderson, Craig S. (Lippincott Williams & Wilkins, 2017)
      Background and Purpose-Many patients receiving thrombolysis for acute ischemic stroke are on prior antiplatelet therapy (APT), which may increase symptomatic intracerebral hemorrhage risk. In a prespecified subgroup analysis, ...