Browsing by Author "6a83d133-7a81-4c9d-8de6-0e4272748c3a"
Now showing items 1-4 of 4
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Pérez, María José; Ponce, Daniela P.; Aranguiz, Alejandra; Behrens Pellegrino, María Isabel; Quintanilla, Rodrigo A. (Elsevier B.V., 2018)© 2018 The Authors In the last few decades, many reports have suggested that mitochondrial function impairment is a hallmark of Alzheimer's disease (AD). Although AD is a neurodegenerative disorder, mitochondrial damage ...
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Orellana, Daniel I.; Quintanilla, Rodrigo A.; Maccioni Baraona, Ricardo (Elsevier B.V., 2006-10-21)The tumor necrosis factor alpha (TNFα) plays a dual role in producing either neurodegeneration or neuroprotection in the central nervous system. Despite that TNFα was initially described as a cell death inductor, ...
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Quintanilla, Rodrigo A.; Utreras Puratich, Elías; Cabezas Opazo, Fabián A. (Hindawi Publishing Corporation, 2014)© 2014 Rodrigo A. Quintanilla et al.Neuronal processes (neurites and axons) have an important role in brain cells communication and, generally, they are damaged in neurodegenerative diseases. Recent evidence has showed ...
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Orellana, Daniel I.; Quintanilla, Rodrigo A.; González Billault, Christian; Maccioni Baraona, Ricardo (Springer New York LLC, 2005)Recent studies show that inflammation has an active role in the onset of neurodegenerative diseases. It is known that in response to extracellular insults microglia and/or astrocytes produce inflammatory agents. These ...