Browsing by Author "6ac41fc4-b756-4725-bd88-9110e4d7cb28"

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    • High fat diet induced obesity produces spontaneous ventricular arrhythmias and increases the activity of ... 
      Sánchez, Gina; Araneda, Felipe; Peña, Juan Pedro; Finkelstein, José Pablo; Riquelme, Jaime A.; Montecinos, Luis; Barrientos Briones, Genaro; Llanos Vidal, Paola; Pedrozo Cibils, Zully; Said, Matilde; Bull Simpfendorfer, Ricardo; Donoso Laurent, Paulina (MDPI, 2018)
      Ventricular arrhythmias are a common cause of sudden cardiac death, and their occurrence is higher in obese subjects. Abnormal gating of ryanodine receptors (RyR2), the calcium release channels of the sarcoplasmic reticulum, ...
    • Ischemia Enhances Activation by Ca2+ and Redox Modification of Ryanodine Receptor Channels from Rat Brain Cortex 
      Bull Simpfendorfer, Ricardo; Finkelstein, José Pablo; Gálvez, Jorge; Sánchez, Gina; Donoso Laurent, Paulina; Behrens Pellegrino, María Isabel; Hidalgo Tapia, María Cecilia (2008)
      Cerebral ischemia stimulates Ca2+influx and thus increases neuronal intracellular free [Ca2+. Using a rat model of cerebral ischemia without recirculation, we tested whether ischemia enhances the activation by Ca2+ of ...