Browsing by Author "6be1d9f7-645d-4990-a317-3471569ab82a"
Now showing items 1-10 of 10
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Casanello, Paola; Schneider, Daniela; Herrera, Emilio A.; Uauy Dagach-Imbarack, Ricardo; Krause, Bernardo J. (Frontiers Media SA, 2014)The endothelium is a multifunctional heterogeneous tissue playing a key role in the physiology of every organ. To accomplish this role the endothelium presents a phenotypic diversity that is early prompted during vascular ...
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Epigenetic Programming of Cardiovascular Disease by Perinatal Hypoxia and Fetal Growth Restriction Casanello, Paola; Herrera Videla, Emilio; Krause, Bernardo J. (INTECH, 2017)Most of the worldwide deaths in patients with non-communicable diseases are due to cardiovascular and metabolic diseases, which are determined by a mix of environmental, genetic and epigenetic factors, and by their ...
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Cañas, Daniel; Herrera, Emilio A.; García-Herrera, Claudio; Celentano, Diego; Krause, Bernardo J. (Frontiers Research Foundation, 2017)© 2017 Cañas, Herrera, García-Herrera, Celentano and Krause. Aim: Fetal growth restriction (FGR) is associated with a variety of cardiometabolic diseases in adulthood which could involve remodeling processes of the vascular ...
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Muñoz Muñoz, Estefanía del Carmen; Krause, Bernardo J.; Uauy Dagach-Imbarack, Ricardo; Casanello, Paola (Wiley-Liss Inc., 2018)© 2018 Wiley Periodicals, Inc. Maternal obesity is associated with large-for-gestational-age (LGA) neonates and programming of obesity-related cardiovascular disease in the offspring, however, the mechanisms that lead to ...
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Herrera, Emilio A.; Riquelme, Raquel A.; Ebensperger Darrouy, Germán; Reyes, Roberto V.; Ulloa, César E.; Cabello, Gertrudis; Krause, Bernardo J.; Parer, Julian T.; Giussani, Dino A.; Llanos Mansilla, Jorge (2010)We determined whether postnatal pulmonary hypertension induced by 70% of pregnancy at high altitude (HA) persists once the offspring return to sea level and investigated pulmonary vascular mechanisms operating under these ...
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Cañas, Daniel; García-Herrera, Claudio M.; Herrera, Emilio A.; Celentano, Diego J.; Krause, Bernardo J. (Elsevier Ltd, 2018)© 2018 Fetal growth restriction (FGR) is a perinatal condition associated with a low birth weight that results mainly from maternal and placental constrains. Newborns affected by this condition are more likely to develop ...
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Herrera, Emilio A.; Cifuentes Zúñiga, Francisca; Figueroa, Esteban; Villanueva, Cristian; Hernández, Cherie; Alegría, René; Arroyo Jousse, Viviana; Peñaloza, Estefania; Farías, Marcelo; Uauy Dagach-Imbarack, Ricardo; Casanello, Paola; Krause, Bernardo J. (Blackwell Publishing Ltd, 2017)© 2016 The Authors. The Journal of Physiology © 2016 The Physiological SocietyKey points: Intrauterine growth restriction (IUGR) is associated with vascular dysfunction, oxidative stress and signs of endothelial epigenetic ...
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Cáceres Rojas, Gabriela; Salamanca, Carlos; Krause, Bernardo J.; Recabarren, Andrea S.; Recabarren, Pamela; Pantoja Parada, Pedro; Leiva Villagra, Noemi; Pardo Vargas, Rosa; Santos, José Luis; Suazo Sanhueza, José Lorenzo (Future Medicine, 2020)Aim: To evaluate the risk of nonsyndromic orofacial clefts (NSOFCs) associated with LINE-1 methylation, as a marker of global DNA methylation, and the effect of MTHFR functional variants on this variable. Patients & methods: ...
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Lopez-Tello, Jorge; Jimenez-Martinez, Maria Angeles; Herrera, Emilio A.; Krause, Bernardo J.; Sferruzzi-Perri, Amanda N. (W.B. Saunders Ltd, 2018)© 2018 Elsevier Ltd Intrauterine growth restriction (IUGR) is a common obstetric complication with immediate and life-long consequences for offspring health. Yet the mechanisms underlying its aetiology require elucidation. ...
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Stim-activated TRPC-ORAI channels in pulmonary hypertension induced by chronic intermittent hypoxia Castillo Galán, Sebastián; Arenas, Germán A.; Reyes, Roberto V.; Krause, Bernardo J.; Iturriaga, Rodrigo (SAGE, 2020)Obstructive sleep apnea (OSA), a breathing disorder featured by chronic intermittent hypoxia (CIH) is associated with pulmonary hypertension (PH). Rodents exposed to CIH develop pulmonary vascular remodeling and PH, but ...