Browsing by Author "6c97098e-a143-41a4-8429-40fa4bdec679"

Now showing items 1-8 of 8

    • Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles 
      Morales Montecinos, Javier; Brayden, David J. (Elsevier, 2017)
      Buccal delivery of macromolecules (biologics) sets a great challenge for researchers. Although several niche small molecule products have been approved as simple sprays, tablets and oral films, it is not simply a case of ...
    • Drug-loaded lipid-core micelles in mucoadhesive films as a novel dosage form for buccal administration of ... 
      Chou, Wai-Houng; Galaz, Ariel; Jara, Miguel O.; Gamboa, Alexander; Morales Montecinos, Javier (MDPI, 2020)
      The aim of the study was to develop a novel buccal dosage form to transport rhodamine 123 and human insulin as models for poorly water-soluble and biological drugs, using lipid-core micelles (LCMs)-loaded mucoadhesive ...
    • Effect of surfactants and drug load on physico mechanical and dissolution properties of nanocrystalline ... 
      Vuddanda, Parameswara Rao; Montenegro Nicolini, Miguel; Morales Montecinos, Javier; Velaga, Sitaram (Elsevier, 2017)
      The aim of the present work was to prepare tadalafil (TDF) nanocrystals-loaded oral polymeric films (OFs) and investigate the effect of hydrophilic surfactants and drug loads on the physico-mechanical and dissolution ...
    • Light-induced release of the cardioprotective peptide angiotensin-(1-9) from thermosensitive liposomes with ... 
      Bejarano, Julián; Rojas, Aldo; Ramírez Sagredo, Andrea; Riveros Salvatierra, Ana; Morales Zavala, Francisco; Flores, Yvo; Riquelme Meléndez, Jaime; Guzmán, Fanny; Araya, Eyleen; Chiong Lay, Mario; Ocaranza, María Paz; Morales Montecinos, Javier; Villamizar Sarmiento, María Gabriela; Sánchez Vergara, Gina; Lavandero González, Sergio; Kogan, Marcelo J. (Elsevier, 2020)
      Angiotensin-(1-9), a component of the non-canonical renin-angiotensin system, has a short half-life in blood. This peptide has shown to prevent and/or attenuate hypertension and cardiovascular remodeling. A controlled ...
    • Morin Flavonoid Adsorbed on Mesoporous Silica, a Novel Antioxidant Nanomaterial 
      Arriagada, Francisco; Correa Briones, Olosmira; Günther Sapunar, Germán; Nonell, Santi; Mura Mardones, Francisco; Olea Azar, Claudio; Morales Montecinos, Javier (Public Library Science, 2016)
      Morin (2' A, 3, 4' , 5,7-pentahydroxyflavone) is a flavonoid with several beneficial health effects. However, its poor water solubility and it sensitivity to several environmental factors avoid its use in applications like ...
    • Poly-epsilon-caprolactone Nanoparticles Loaded with 4-Nerolidylcatechol (4-NC) for Growth Inhibition of ... 
      Greatti, Vanessa Raquel; Oda, Fernando; Sorrechia, Rodrigo; Kapp, Bárbara Regina; Seraphim, Carolina Manzato; Villas Boas Weckwerth, Ana Carolina; Chorilli, Marlus; Da Silva, Patricia Bento; Eloy, Josimar O.; Kogan, Marcelo J.; Morales Montecinos, Javier; Linhari Rodrigues Pietro, Rosemeire Cristina (MDPI, 2020)
      Dermatophyte fungal infections are difficult to treat because they need long-term treatments. 4-Nerolidylcatechol (4-NC) is a compound found in Piper umbellatum that has been reported to demonstrate significant antifungal ...
    • Selected abstracts from Excipient Fest 2017 
      McConville, Jason T.; Morales Montecinos, Javier (Taylor & Francis, 2018)
    • Structuration in the Interface of Direct and Reversed Micelles of Sucrose Esters, Studied by Fluorescent Techniques 
      Sandoval Altamirano, Catalina Paz; Ortega Moreno, Anakenna Dennis; Sánchez, Susana A.; Morales Montecinos, Javier; Günther Sapunar, Germán (Public Library of Science, 2015)
      Reactors found in nature can be described as micro-heterogeneous systems, where media involved in each micro-environment can behave in a markedly different way compared with the properties of the bulk solution. The ...