Browsing by Author "6ca7cc25-b809-4561-811c-63e8b833fcee"

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    • Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells ... 
      Jara, Claudia; Oyarzún Ampuero, Felipe; Carrión, Flavio; González Echeverría, Esteban; Cappelli, Claudio; Caviedes Fernández, Pablo (BMC, 2020)
      Background: In type I diabetes mellitus (T1DM) pancreatic beta cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet ...
    • Ski Is required for tri-methylation of H3K9 in major satellite and for repression of pericentromeric genes: ... 
      Cappelli, Claudio; Sepúlveda, Hugo; Rivas Vera, Solange; Pola Véliz, Víctor; Urzúa Tobar, Ulises; Donoso Luna, Gerardo; Sagredo Campos, Eduardo; Carrero Zapata, David; Casanova Ortiz, Emmanuel; Sagredo Campos, Alfredo; González Vergara, Marisel; Manterola Zúñiga, Marcia; Nardocci, Gino; Armisén Yañez, Ricardo; Montecino, Martín; Marcelain Cubillos, Katherine (Elsevier, 2020)
      Several mechanisms directing a rapid transcriptional reactivation of genes immediately after mitosis have been described. However, little is known about the maintenance of repressive signals during mitosis. In this work, ...