Browsing by Author "6cbe7bdb-deee-40c7-93c2-379fe9f55716"

Now showing items 1-6 of 6

    • A Multi-Serotype Approach Clarifies the Catabolite Control Protein A Regulon in the Major Human Pathogen ... 
      DebRoy, Sruti; Saldaña, Miguel; Travisany, Dante; Montano, Andrew; Galloway Peña, Jessica; Horstmann, Nicola; Yao, Hui; González Canales, Mauricio; Maass Sepúlveda, Alejandro; Latorre Mora, Mauricio; Shelburne, Samuel (Nature Publishing Group, 2016)
      Catabolite control protein A (CcpA) is a highly conserved, master regulator of carbon source utilization in gram-positive bacteria, but the CcpA regulon remains ill-defined. In this study we aimed to clarify the CcpA regulon ...
    • Genome-scale metabolic models of Microbacterium species isolated from a high altitude desert environment 
      Mandakovic, Dinka; Cintolesi, Ángela; Maldonado, Jonathan; Mendoza, Sebastián; Aite, Meziane; Gaete, Alexis; Saitua, Francisco; Allende, Miguel; Cambiazo Ayala, Liliana; Siegel, Anne; Maass Sepúlveda, Alejandro; González Canales, Mauricio; Latorre Mora, Mauricio (Nature, 2020)
      The Atacama Desert is the most arid desert on Earth, focus of important research activities related to microbial biodiversity studies. In this context, metabolic characterization of arid soil bacteria is crucial to understand ...
    • Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human ... 
      DebRoy, Sruti; Aliaga Tobar, Víctor; Gálvez, Gabriel; Arora, Srishtee; Liang, Xiaowen; Horstmann, Nicola; Maracajá Coutinho, Vinicius; Latorre Mora, Mauricio; Hook, Magnus; Flores, Anthony; Shelburne, Samuel A. (Wiley, 2020)
      Catabolite control protein A (CcpA) is a master regulator of carbon source utilization and contributes to the virulence of numerous medically important Gram-positive bacteria. Most functional assessments of CcpA, including ...
    • Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency 
      Acuña, Mariana; Castro Fernández, Víctor; Latorre Mora, Mauricio; Castro, Juan; Schuchman, Edward H.; Guixé Leguía, Victoria Cristina; González Canales, Mauricio; Zanlungo, Silvana (Elsevier, 2016)
      Niemann-Pick disease (NPD) type A and B are recessive hereditary disorders caused by deficiency in acid sphingomyelinase (ASM). The p.A1a359Asp mutation has been described in several patients but its functional and structural ...
    • Structure and co-occurrence patterns in microbial communities under acute environmental stress reveal ... 
      Mandakovic Seyler, Dinka; Rojas, Claudia; Maldonado, Jonathan; Latorre Mora, Mauricio; Travisany, Dante; Delage, Erwan; Bihouee, Audrey; Jean, Geraldine; Díaz, Francisca; Fernández Gómez, Beatriz; Cabrera, Pablo; Gaete, Alexis; Latorre, Claudio; Gutiérrez, Rodrigo A.; Maass Sepúlveda, Alejandro; Cambiazo Ayala, Liliana; Navarrete, Sergio A.; Eveillard, Damien; González Canales, Mauricio (Nature Publishing Group, 2018)
      Understanding the factors that modulate bacterial community assembly in natural soils is a longstanding challenge in microbial community ecology. In this work, we compared two microbial co-occurrence networks representing ...
    • The bioleaching potential of a bacterial consortium 
      Latorre Mora, Mauricio; Cortés Burgos, María Paz; Travisany, Dante; Di Genova, Alex; Budinich Abarca, Marko; Reyes Jara, Angélica; Hödar Quiroga, Christian; González Canales, Mauricio; Parada, Pilar; Bobadilla Fazzini, Roberto; Cambiazo Ayala, Liliana; Maass Sepúlveda, Alejandro (Elsevier, 2016)
      This work presents the molecular foundation of a consortium of five efficient bacteria strains isolated from copper mines currently used in state of the art industrial-scale biotechnology. The strains Acidithiobacillus ...