Browsing by Author "6dfa9f38-c7fa-44b1-b741-504217b05e36"

Now showing items 1-3 of 3

    • Analysis of the characteristics and components for the frailty syndrome in older adults from central Chile. ... 
      Palomo, Iván; Giacaman, Rodrigo; León, Soraya; Lobos, German; Bustamante, Miguel; Wehinger, Sergio; Tapia, Juan; Fuentes, Manuel; Alarcón, Marcelo; García, Francisco; Albala Brevis, Cecilia; Fuentes, Eduardo (Elsevier Ireland Ltd, 2019)
      Objective: To determine the prevalence and to characterize frailty in elderly subjects in four urban provincial capitals and two rural communes from Maule Region in Chile. Design: Cross-sectional study. Participants: 1205 ...
    • Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1 alpha S-Nitrosylation and Transcriptional ... 
      Sanhueza, Carlos; Castillo Bennett, Jimena; Valenzuela Valderrama, Manuel; Contreras, Pamela; Lobos González, Lorena; Campos, América; Wehinger, Sergio; Lladser, Álvaro; Kiessling, Rolf; Leyton Campos, Lisette; Quest, Andrew F. G. (MDPI, 2020)
      Caveolin-1 (CAV1) is a well-established nitric oxide synthase inhibitor, whose function as a tumor suppressor is favored by, but not entirely dependent on, the presence of E-cadherin. Tumors are frequently hypoxic and the ...
    • Loss of caveolin-1 is associated with a decrease in beta cell death in mice on a high fat diet 
      Lillo Urzúa, Paloma; Núñez Murillo, Olinda; Castro Sepúlveda, Mauricio; Torres Quintana, María Angélica; Lladser Caldera, Álvaro; Quest, Andrew F. G.; Espinoza Robles, Carolina; Llanos Vidal, Paola; Wehinger, Sergio (MDPI, 2020)
      Elevated free fatty acids (FFAs) impair beta cell function and reduce beta cell mass as a consequence of the lipotoxicity that occurs in type 2 diabetes (T2D). We previously reported that the membrane protein caveolin-1 ...