Browsing by Author "7249e702-509b-42fa-a3d2-13a5a18cd535"

Now showing items 1-10 of 10

    • Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells ... 
      García González, Paulina; Schinnerling, Katina; Sepúlveda Gutierrez, Alejandro; Maggi, Jaxaira; Mehdi, Ahmed M.; Nel, Hendrik J.; Pesce Reyes, Bárbara; Larrondo Lillo, Milton; Aravena, Octavio; Molina Sampayo, María Carmen; Catalán Martina, Diego; Thomas, Ranjeny; Verdugo Salgado, Ricardo; Aguillón Gutiérrez, Juan Carlos (Frontiers Media SA, 2017)
      There is growing interest in the use of tolerogenic dendritic cells (tolDCs) as a potential target for immunotherapy. However, the molecular bases that drive the differentiation of monocyte-derived DCs (moDCs) toward a ...
    • Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic ... 
      Maggi, Jaxaira; Schinnerling, Katina; Pesce Reyes, Bárbara; Hilkens, Catharien M.; Catalán Martina, Diego; Aguillón Gutiérrez, Juan Carlos (Frontiers Media, 2016)
      Tolerogenic dendritic cells (DCs) are a promising tool to control T cell-mediated autoimmunity. Here, we evaluate the ability of dexamethasone-modulated and monophosphoryl lipid A (MPLA)-activated DCs [MPLA-tolerogenic DCs ...
    • Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients ... 
      García González, P. A.; Schinnerling, Katina; Sepúlveda A., Jocelyne; Ubilla Olguín, Gabriela; Soto, L.; Neira Quiroga, Oscar; Medhi, A. M.; Nel, H. J.; Catalán Martina, Diego; Thomas, R. C.; Verdugo Salgado, Ricardo; Aguillón Gutiérrez, Juan Carlos (2016)
    • Humanized mouse models of rheumatoid arthritis for studies on immunopathogenesis and preclinical testing ... 
      Schinnerling, Katina; Rosas, Carlos; Soto, Lilian; Thomas, Ranjeny; Aguillón, Juan Carlos (Frontiers Media S.A., 2019)
      Copyright © 2019 Schinnerling, Rosas, Soto, Thomas and Aguillón. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other ...
    • Peripheral T-Cell reactivity to heat shock protein 70 and its cofactor GrpE from tropheryma whipplei is ... 
      Trotta, Lucia; Weigt, Kathleen; Schinnerling, Katina; Geelhaar Karsch, Anika; Oelkers, Gerrit; Biagi, Federico; Corazza, Gino Roberto; Allers, Kristina; Schneider, Thomas; Erben, Ulrike; Moos, Verena (American Society for Microbiology, 2017)
      Classical Whipple's disease (CWD) is characterized by the lack of specific Th1 response toward Tropheryma whipplei in genetically predisposed individuals. The cofactor GrpE of heat shock protein 70 (Hsp70) from T. whipplei ...
    • Regulation of tolerogenic features on dexamethasone-modulated MPLA-activated dendritic cells by Myc 
      García González, Paulina; Maggi, Jaxaira; Schinnerling, Katina; Sepúlveda Gutiérrez, Alejandro; Soto, Lilian; Neira, Oscar; Mehdi, Ahmed M.; Nel, Hendrik J.; Pesce, Bárbara; Aravena, Octavio; Molina, María Carmen; Catalán, Diego; Thomas, Ranjeny; Verdugo Salgado, Ricardo (Frontiers Media S.A., 2019)
      Copyright © 2019 García-González, Maggi, Schinnerling, Sepúlveda-Gutiérrez, Soto, Neira, Mehdi, Nel, Pesce, Aravena, Molina, Catalán, Thomas, Verdugo and Aguillón.The potential of tolerogenic dendritic cells (tolDCs) to ...
    • The role of interleukin-6 signalling and its therapeutic blockage in skewing the T cell balance in rheumatoid ... 
      Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego; Soto Sáez, Lilian (Wiley, 2017)
      Therapeutic blockage of cytokine signalling in autoimmune diseases has improved our understanding of the role of these cytokines in triggering, shaping and perpetuating autoimmune responses. In rheumatoid arthritis (RA), ...
    • Therapeutic potential of hyporesponsive CD4+ T cells in autoimmunity 
      Maggi, Jaxaira; Schafer, Carolina; Ubilla Olguín, Gabriela; Catalán Martina, Diego; Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos (Frontiers Media S.A., 2015)
      © 2015 Maggi, Schafer, Ubilla-Olguín, Catalán, Schinnerling and Aguillón. The interaction between dendritic cells (DCs) and T cells is crucial on immunity or tolerance induction. In an immature or semi-mature state, DCs ...
    • Tolerogenic dendritic cells for reprogramming of lymphocyte responses in autoimmune diseases 
      García González, Paulina; Ubilla Olguín, Gabriela; Catalán Martina, Diego; Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos (Elsevier, 2016)
      Dendritic cells (DCs) control immune responses by driving potent inflammatory actions against external and internal threats while generating tolerance to self and harmless components. This duality and their potential to ...
    • Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures ... 
      García González, Paulina; Schinnerling, Katina; Sepúlveda Gutiérrez, Alejandro; Maggi, Jaxaira; Hoyos, Lorena; Morales, Rodrigo; Mehdi, Ahmed; Nel, Hendrik; Soto Sáez, Lilian; Pesce Reyes, Bárbara; Molina Sampayo, María Carmen; Cuchacovich Turteltaub, Miguel; Larrondo Lillo, Milton; Neira, Oscar; Catalán Martina, Diego; Hilkens, Catharien M.; Thomas, Ranjeny; Verdugo Salgado, Ricardo; Aguillón Gutiérrez, Juan Carlos (Frontiers Media, 2016-10-25)
      Tolerogenic dendritic cells (TolDCs) are promising tools for therapy of autoimmune diseases, such as rheumatoid arthritis (RA). Here, we characterize monocyte-derived TolDCs from RA patients modulated with dexamethasone ...