Browsing by Author "74966e70-0216-4967-a5ee-a90195d3ce28"

Now showing items 1-7 of 7

    • Bioactive Compounds as PPARs Ligands: Potential Health Effects 
      Reyna Gallegos, Sixto Leonardo; Echeverría González, Francisca (2019-03)
      Peroxisome proliferator-activated receptors (PPARs) are transcription factors whose isoforms (α, β/δ, and γ) have key and complementary roles in relation to energy metabolism, glucose and lipid homeostasis, regulation of ...
    • Docosahexaenoic acid (DHA), a fundamental fatty acid for the brain: new dietary sources 
      Echeverría González, Francisca; Valenzuela Báez, Rodrigo; Hernández Rodas, María Catalina; Valenzuela Bonomo, Carlos (Elsevier, 2017)
      Docosahexaenoic acid (C22: 6n-3, DHA) is a long-chain polyunsaturated fatty acid of marine origin fundamental for the formation and function of the nervous system, particularly the brain and the retina of humans. It has ...
    • Hydroxytyrosol and cytoprotection: a projection for clinical interventions 
      Echeverría González, Francisca; Ortíz, Macarena; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (MDPI AG, 2017)
      Hydroxytyrosol (HT) ((3,4-Dihydroxyphenyl) ethanol) is a polyphenol mainly present in extra virgin olive oil (EVOO) but also in red wine. It has a potent antioxidant effect related to hydrogen donation, and the ability to ...
    • Hydroxytyrosol prevents reduction in liver activity of Delta - 5 and Delta - 6 desaturases, oxidative stress, ... 
      Valenzuela Báez, Rodrigo; Echeverría González, Francisca; Ortíz, Macarena; Rincón Cervera, Miguel Ángel; Espinosa Escalona, Berta; Hernández Rodas, María Catalina; Illesca, Paola; Valenzuela Bonomo, Carlos; Videla Cabrera, Luis (Biomed Central Ltd., 2017)
      Background: Eicosapentaenoic acid (EPA, C20:5n-3), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (AA, C20:4n-6) are long-chain polyunsaturated fatty acids (LCPUFAs) with relevant roles in the organism. EPA and ...
    • Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging 
      Echeverría González, Francisca; Ortiz, Macarena; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (Elsevier, 2016)
      Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that function as ligand-dependent transcription factors that can be activated by different types of fatty acids (FAs). Three isoforms of PPARs have ...
    • Modulation of PPARs in Health and Disease: Role of Fatty Acids 
      Ortiz, Macarena; Echeverría González, Francisca; Valenzuela Báez, Rodrigo; Videla Cabrera, Luis (2019-03)
    • Protective effects of eicosapentaenoic acid plus hydroxytyrosol supplementation against white adipose tissue ... 
      Illesca, Paola; Valenzuela Báez, Rodrigo; Espinosa, Alejandra; Echeverría González, Francisca; Soto Alarcón, Sandra; Campos, Cristian; Rodríguez, Alicia; Vargas, Romina; Magrone, Thea; Videla Cabrera, Luis Alaberto (MDPI, 2020)
      Objective: Obesity induced by high-fat diet (HFD) elicits white adipose tissue dysfunction. In this study, we have hypothesized that the metabolic modulator eicosapentaenoic acid (EPA) combined with the antioxidant ...