Browsing by Author "76458892-eb0e-49b2-b4fc-fe90e05b0828"

Now showing items 1-10 of 10

    • DNA methylation in promoter regions of genes involved in the reproductive and metabolic function of children ... 
      Echiburú López, Bárbara; Milagro, Fermín; Crisosto King, Nicolás; Pérez Bravo, Francisco; Flores Ramírez, Cristián; Arpón, Ana; Salas Pérez, Francisca; Recabarren, Sergio E.; Sir-Petermann, Teresa; Maliqueo, Manuel (Taylor & Francis, 2020)
      Clinical and experimental evidences indicate that epigenetic modifications induced by the prenatal environment are related to metabolic and reproductive derangements in polycystic ovary syndrome (PCOS). Alterations in the ...
    • Epigenética del síndrome de ovario poliquístico 
      Concha C., Francisca; Sir Petermann, Lidia; Recabarren, Sergio E.; Pérez Bravo, Fernando (Sociedad Médica de Santiago, 2017)
      Polycystic ovarian syndrome (PCOS) is an endocrine and metabolic dysfunction, highly prevalent in women in their reproductive years. Hyperandrogenism, oligo-ovulation, polycystic ovarian morphology are the main features ...
    • Increased anti-müllerian hormone serum concentrations in prepubertal daughters of women with polycystic ... 
      Sir Petermann, Teresa; Codner Dujovne, Ethel; Maliqueo Yevilao, Manuel; Echiburú López, Bárbara; Hitschfeld, Catalina; Crisosto King, Nicolás; Pérez Bravo, Francisco; Recabarren, Sergio E.; Cassorla Goluboff, Fernando (Endocrine Society, 2006)
      Context: Anti-Müllerian hormone (AMH) is produced by the granulosa cells and reflects follicular development. Adult women with polycystic ovary syndrome (PCOS) have increased levels of AMH associated with an excessive ...
    • Long-term testosterone treatment during pregnancy does not alter insulin or glucose profile in a sheep model ... 
      Recabarren, Monica; Carrasco, Albert; Sandoval, Daniel; Diaz, Felipe; Sir Petermann, Teresa; Recabarren, Sergio E. (Taylor and Francis Ltd, 2019)
      © 2017, © 2017 Informa UK Limited, trading as Taylor & Francis Group.The administration of testosterone to pregnant sheep to resemble fetal programming of the polycystic ovary syndrome could alter other hormones/factors ...
    • Metabolic profile in sons of women with polycystic ovary syndrome 
      Recabarren, Sergio E.; Smith, Rosita; Rios, Rafael; Maliqueo Yevilao, Manuel; Echiburú López, Bárbara; Codner Dujovne, Ethel; Cassorla Goluboff, Fernando; Rojas, Pedro; Sir Petermann, Teresa (Endocrine Society, 2008)
      Context: Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disorder with strong familial aggregation. It has been demonstrated that parents and brothers of PCOS women exhibit insulin resistance and related ...
    • Prenatal exposure to androgens as a factor of fetal programming La exposición prenatal a andrógenos como ... 
      Recabarren, Sergio E.; Sir Petermann, Teresa; Maliqueo Yevilao, Manuel; Lobos, Alejandro; Rojas García, Pedro (2006)
      Both epidemiological and clinical evidence suggest a relationship between the prenatal environment and the risk of developing diseases during adulthood. The first observations about this relationship showed that prenatal ...
    • Prenatal testosterone excess alters Sertoli and germ cell number and testicular FSH receptor expression in rams 
      Rojas García, Pedro; Recabarren, Mónica P.; Sarabia, Luis; Schön, Jennifer; Gabler, Christoph; Einspanier, Ralf; Maliqueo Yevilao, Manuel; Sir Petermann, Teresa; Rey, Rodolfo; Recabarren, Sergio E. (2010)
      Exposure to excess testosterone (T) during fetal life has a profound impact on the metabolic and reproductive functions in the female's postnatal life. However, less is known about the effects of excess testosterone in ...
    • Prenatal testosterone exposure disrupts Insulin secretion and promotes insulin resistance 
      Carrasco, Albert; Recabarren, Mónica P.; Rojas García, Pedro P.; Gutiérrez, Mario; Morales, Karina; Sir Petermann, Teresa; Recabarren, Sergio E. (Nature, 2020)
      Hyperandrogenemia and metabolic disturbances during postnatal life are strongly linked both to polycystic ovary syndrome and other conditions that arise from prenatal exposure to androgen excess. In an animal model of this ...
    • Prenatal testosterone treatment alters LH and testosterone responsiveness to GnRH agonist in male sheep 
      Recabarren, Sergio E.; Lobos, Alejandro; Figueroa, Yara; Padmanabhan, Vasantha; Foster, Douglas L.; Sir Petermann, Teresa (Society of Biology of Chile, 2007)
      Although evidence is accumulating that prenatal testosterone (T) compromises reproductive function in the female, the effects of excess T in utero on the postnatal development of male reproductive function has not been ...
    • Secretory patterns of leptin and luteinizing hormone in food-restricted young female sheep 
      Recabarren, Sergio E.; Lobos, Alejandro; Torres, Verónica; Oyarzo, Roberto; Sir Petermann, Teresa (Society of Biology of Chile, 2004)
      Leptin, the product of the ob gene, has been proposed as a metabolic signal that regulates the secretion of GnRH/LH. This may be critical during prepubertal development to synchronize information about energy stores and ...