Browsing by Author "76f6c0b1-8524-4074-84ae-58c9b25db3d8"
Now showing items 1-18 of 18
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Herreros, Eduardo; Morales, Sebastián; Cortés, Cristian; Cabaña, Mauricio; Peñaloza, Juan P.; Jara, Lilian; Geraldo, Daniela; Otero, Carolina; Fernández-Ramires, Ricardo (Bentham Science Publishers B.V., 2014)© 2014, Bentham Science Publishers. Recent advances in nanotechnology and nanobiotechnology have contributed to the development of nanomaterials, able to be used as drug carriers, probes, targets or cytostatic drugs by ...
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Jara, Lilian; Ampuero Llanos, Sandra; Seccia, Lorena; Bustamante, Mario; Blanco, Rafael; Ojeda, José Manuel (2002)Breast cancer is the most common malignancy among women. Chilean studies reveal that this cancer presents the third highest mortality rate. A family history of breast cancer is one of the major risk factors for the development ...
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Suazo, José; Santos, José Luis; Jara, Lilian; Blanco, Rafael (Brazilian Journal of Genetics, 2008)Nonsyndromic cleft lip/palate (NSCLP) is a congenital malformation with features of a complex genetic trait. Several studies have reported positive association and linkage between NSCLP and microsatellite markers in the ...
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Quappe, Leticia; Jara, Lilian; López, Néstor (2004)Background: Genetic polymorphisms for interleukin (IL)- 1α and - 1β have been proposed as potential genetic markers for periodontal diseases. Since the prevalence of these polymorphisms could be race-related, and no data ...
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López, Néstor; Jara, Lilian; Valenzuela, Carlos (2005)Background: Several studies have investigated genetic polymorphisms for cytokines as potential genetic markers for periodontitis. Some studies have found that interleukin (IL)-1A and IL-1B polymorphisms are associated with ...
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Blanco, Rafael; Arcos-Burgos, Mauricio; Paredes, Mónica; Palomino, Hernán; Jara, Lilian; Carreño, Hernán; Obreque, Victor; Muñoz, M. A. (Brazilian Journal of Genetics, 1998)The contemporary urban mixed Chilean population stems from the admixture of the native Amerindians with the Spaniards, showing an average incidence rate of nonsyndromic cleft lip with or without cleft palate (NSCLP) of 1.8 ...
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López, Néstor J.; Quintero, Antonio; Llancaqueo, Marcelo; Jara, Lilian (2009)Background: Studies investigating effects of periodontal treatment (PT) on markers of inflammation in healthy subjects show conflicting results. Few studies have investigated the effects of PT among subjects with coronary ...
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Jara, Lilian; Ampuero Llanos, Sandra; Seccia, Lorena; Bustamante, Mario; Blanco, Rafael; Santibáñez, Eudocia; Reyes, José Miguel; Ojeda, José Manuel (2002)BACKGROUND: Breast cancer is the most common malignancy among women, and is the second cause of cancer mortality among Chilean women. Female mortality due to breast cancer in Chile has shown a steady increase from 9.5 ...
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Villanueva, Pia; Newbury, Dianne F.; Jara, Lilian; Barbieri Ortiz, Zulema de,; Mirza, Ghazala; Palamino, Hernán M.; Fernández, María Angélica; Cazier, Jean Baptiste; Monaco, Anthony P.; Palomino, Hernán (2011)Specific language impairment (SLI) is an unexpected deficit in the acquisition of language skills and affects between 5 and 8% of pre-school children. Despite its prevalence and high heritability, our understanding of the ...
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López, Néstor; Valenzuela, Carlos; Jara, Lilian (2009)Background: Epidemiologic studies have shown an increased frequency, severity, and risk of periodontitis in patients with diabetes. Periodontitis is associated with certain interleukin (IL)-1 gene cluster polymorphisms. ...
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Jara, Lilian; Ampuero Llanos, Sandra; Santibáñez, Eudocia; Seccia, Lorena; Rodríguez, Juan; Bustamante, Mario; Lay-Son, Guillermo; Ojeda, José Manuel; Reyes, José Miguel; Blanco, Rafael (Society of Biology of Chile, 2004)BRCA1 gene mutations account for nearly all families with multiple cases of both early onset breast and/or ovarian cancer and about 30% of hereditary breast cancer. Although to date more than 1,237 distinct mutations, ...
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Suazo, José; Santos, José Luis; Jara, Lilian; Blanco, Rafael (2010)Based on association and sequencing studies, investigators have postulated muscle segment homeobox 1 (MSX1) as a strong candidate gene involved in the causation of nonsyndromic cleft lip with or without cleft palate (NSCLP). ...
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González Hormazábal, Patricio; Retamales Ortega, Rocío; Musleh Katan, Maher; Bustamante, Marco; Stambuk, Juan; Pisano, Raúl; Valladares Hernández, Héctor; Lanzarini Sobrevía, Enrique; Chiong Tello, Héctor; Suazo, José; Quiñones Sepúlveda, Luis; Varela Figueroa, Nelson; Castro, Gonzalo; Jara, Lilian; Verdugo Salgado, Ricardo; Berger, Zoltan (Springer, 2020)Genetic variants are considered risk factors for gastric cancer. To date, 61 polymorphisms have been identified as associated with this disease. The aim of the present study was to analyze the association of some of those ...
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González Hormazábal, Patricio; Musleh Katan, Maher; Escandar, S.; Valladares Hernández, Héctor; Lanzarini Sobrevia, Enrique; Castro, V. G.; Jara, Lilian; Berger, Zoltan (BMC, 2018-06-20)Background: Current available treatments for Helicobacter pylori eradication are chosen according to local clarithromycin and metronidazole resistance prevalence. The aim of this study was to estimate, by means of molecular ...
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Jara, Lilian; Acevedo, Monica L.; Blanco, Rafael; Castro, Victor G.; Bravo, Teresa; Gómez, Fernando; Waugh, Enrique; Peralta, Octavio; Cabrera, Elsa; Reyes, José M.; Ampuero Llanos, Sandra; González Hormazábal, Patricio (2007)Several studies have reported that mutations in genes involved in maintenance of genome integrity may be responsible for increased cancer risk. Human RAD51, known to function in DNA repair, interacts with a number of ...
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González Hormazábal, Patricio; Musleh, Maher; Bustamante, Marco; Stambuk, Juan; Escandar, Susana; Valladares, Hector; Lanzarini, Enrique; Chiong, Hector; Rojas, Jorge; Castro, V. Gonzalo; Rubio-Reyes, Cristian; Jara, Lilian; Berger, Zoltan (International Institute of Anticancer Research, 2014)Aim: To assess the role of pro- and anti-inflammatory polymorphisms in gastric cancer susceptibility. Patients and Methods: We genotyped 12 polymorphisms in eight cytokine genes (Interleukin-1β-IL1B-, IL8, IL17A, IL17F, ...
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Mountford, Hayley S.; Villanueva Bianchini, Pía; Fernández Gallardo, María Angélica; Jara, Lilian; De Barbieri, Zulema; Carvajal Carmona, Luis G.; Cazier, Jean-Baptiste; Newbury, Dianne F. (Frontiers Media, 2020)Studies examining genetic conditions common in Latin America are highly underrepresented in the scientific literature. Understanding of the population structure is limited, particularly Chile, in part due to the lack of ...
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Jara, Lilian; Dubois, Karen; Gaete, Daniel; De Mayo, Tomas; Ratkevicius, Nikalai; Bravo, Teresa; Margarit, Sonia; Blanco, Rafael; Gómez, Fernando; Waugh, Enrique; Peralta, Octavio; Reyes, Jose M.; Ibáñez, Gladys; González Hormazábal, Patricio (Springer New York, 2010)The double-strand break (DSB) DNA repair pathway has been implicated in breast cancer (BC). RAD51 and its paralogs XRCC3 and RAD51D play an important role in the repair of DSB through homologous recombination (HR). Some ...