Browsing by Author "785ee2a6-282c-4b49-9b5d-b21a94129e7a"

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    • Homeostatic interplay between FoxO proteins and ER proteostasis in cancer and other diseases 
      González Quiroz, Matias; Urra, Hery; Limia, Celia María; Hetz Flores, Claudio (Elsevier, 2018-06)
      Cancer cells are exposed to adverse conditions within the tumor microenvironment that challenge cells to adapt and survive. Several of these homeostatic perturbations insults alter the normal function of the endoplasmic ...
    • When Endoplasmic Reticulum Proteostasis Meets the DNA Damage Response 
      González Quiroz, Matías; Blondel, Alice; Sagredo, Alfredo; Hetz Flores, Claudio; Chevet, Eric; Pedeux, Remy (Elsevier, 2020)
      Sustaining both proteome and genome integrity (GI) requires the integration of a wide range of mechanisms and signaling pathways. These comprise, in particular, the unfolded protein response (UPR) and the DNA damage response ...