Browsing by Author "78fdd9c7-80e1-4bb5-b80e-d91f74c7bb7b"

Now showing items 1-8 of 8

    • Antiangiogenic and antitumor effects of trypanosoma cruzi Calreticulin 
      López, Nandy C.; Valck, Carolina; Ramírez, Galia; Rodríguez, Margarita; Ribeiro, Carolina; Orellana, Juana; Maldonado, Ismael; Albini, Adriana; Anacona, Daniel; Lemus, David; Aguilar, Lorena; Schwaeble, Wilhelm; Ferreira, Arturo (2010)
      Background: In Latin America, 18 million people are infected with Trypanosoma cruzi, the agent of Chagas' disease, with the greatest economic burden. Vertebrate calreticulins (CRT) are multifunctional, intra- and extracellular ...
    • Comparative in vivo antiangiogenic effects of calreticulin from Trypanosoma cruzi and Homo sapiens sapiens 
      Toledo, Víctor; Ramírez, Galia; Valck, Carolina; López, Nandy; Ribeiro, Carolina H.; Maldonado, Ismael; Aguilar, Lorena; Lemus, David; Ferreira, Arturo (Society of Biology of Chile, 2010)
      Angiogenesis is a complex multi-step process of neovascularization arising from preexisting blood vessels whose generation is regulated by pro- and anti-angiogenic factors. Both Trypanosoma cruzi calreticulin (TcCRT) and ...
    • Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection? 
      Abello Cáceres, Paula; Pizarro Bauerle, Javier; Rosas Chuñil, Carlos Alberto; Maldonado, Ismael; Aguilar Guzmán, Lorena Andrea; González Guevara, Carlos Mauricio; Ramírez Toloza, Galia Andrea; Ferreira Parker, Jorge; Ferreira Vigouroux, Luis Arturo (2016)
      Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T. ...
    • In vitro Treatment of a Murine Mammary Adenocarcinoma Cell Line with Recombinant Trypanosoma cruzi Calreticulin ... 
      Sosoniuk Roche, Eduardo Rodrigo; Cruz, Pamela; Maldonado, Ismael; Duaso, Leonora; Pesce Reyes, Bárbara; Michalak, Marek; Valck Calderón, Carolina Eliana; Ferreira Vigouroux, Arturo (Elsevier, 2020)
      American Trypanosomiasis, a parasitic disease produced by Trypanosoma cruzi (T. cruzi), endemic in Latin America, infects about 6 million people. During the chronic stage of the infection, approximately 30% of infected ...
    • Molluskan hemocyanins activate the classical pathway of the human complement system through natural antibodies 
      Pizarro Bauerle, Javier; Maldonado, Ismael; Sosoniuk Roche, Eduardo Rodrigo; Vallejos, Gerardo; López, Mercedes N.; Salazar Onfray, Flavio; Aguilar Guzmán, Lorena Andrea; Valck Calderón, Carolina Eliana; Ferreira, Arturo; Becker, María Inés (Frontiers Research Foundation, 2017)
      © 2017 Pizarro-Bauerle, Maldonado, Sosoniuk-Roche, Vallejos, López, Salazar-Onfray, Aguilar-Guzmán, Valck, Ferreira and Becker. Molluskan hemocyanins are enormous oxygen-carrier glycoproteins that show remarkable ...
    • Triatoma infestans Calreticulin: Gene cloning and expression of a main domain that interacts with the host ... 
      Weinberger, Katherine; Collazo, Norberto; Aguillón Gutiérrez, Juan Carlos; Molina, Mariá Carmen; Rosas, Carlos; Penã, Jaime; Pizarro, Javier; Maldonado, Ismael; Cattan Ayala, Pedro; Apt Baruch, Werner; Ferreira, Arturo (American Society of Tropical Medicine and Hygiene, 2017)
      © 2017 by The American Society of Tropical Medicine and Hygiene.Triatoma infestans is an important hematophagous vector of Chagas disease, a neglected chronic illness affecting approximately 6 million people in Latin ...
    • Trypanosoma cruzi calreticulin: A novel virulence factor that binds complement C1 on the parasite surface ... 
      Ramírez Toloza, Galia; Valck, Carolina; Molina, María C.; Ribeiro, Carolina Hager; López, Nandy; Sánchez, Gittith; Ferreira, Viviana P.; Billetta, Rosario; Aguilar, Lorena; Maldonado, Ismael; Cattan Ayala, Pedro; Schwaeble, Wilhelm; Ferreira Vigouroux, Luis Arturo (Elsevier, 2011)
      In Trypanosoma cruzi, calreticulin (TcCRT) translocates from the endoplasmic reticulum (ER) to the area of flagellum emergence. We propose herein that the parasite uses this molecule to capture complement C1, in an ...
    • Trypanosoma cruzi calreticulin: A possible role in Chagas' disease autoimmunity 
      Ribeiro, Carolina Hager; López, Nandy C.; Ramírez, Galia A.; Valck, Carolina E.; Molina, María Carmen; Aguilar, Lorena; Rodríguez, Margarita; Maldonado, Ismael; Martínez, Ramón; González, Carlos; Troncoso, Rodrigo; Lavandero González, Sergio; Gingras, Alexandre R.; Schwaeble, Wilhelm (2009)
      Trypanosoma cruzi (T. cruzi) is the causative agent of Chagas' disease, an endemic and chronic illness that affects 18 million people in Latin America. The mechanisms underlying its pathogenesis are controversial. There ...