Browsing by Author "7900f224-024d-4558-9c0a-f9c4b7e67687"

Now showing items 1-6 of 6

    • Alveolar bone resorption and TH1/TH17-associated immune response triggered during Aggregatibacter ... 
      Monasterio, Gustavo; Castillo, Francisca; Ibarra, Juan; Guevara, José; Rojas, Leticia; Alvarez, Carla; Fernández, Baltasar; Agüero, Amaru; Betancur, Daniel; Vernal Astudillo, Rolando (Wiley-Blackwell, 2018)
      BACKGROUND: Aggregatibacter actinomycetemcomitans expresses several virulence factors that may contribute to the pathogenesis of periodontitis. Based on the antigenicity of the O-polysaccharide component of the ...
    • Capsular-defective Porphyromonas gingivalis mutant strains induce less alveolar bone resorption than W50 ... 
      Monasterio, Gustavo; Fernández, Baltasar; Castillo, Francisca; Rojas, Carolina; Cafferata, Emilio A.; Rojas, Leticia; Alvarez, Carla; Fernández, Alejandra; Hernández, Marcela; Bravo, Denisse; Vernal Astudillo, Rolando (Wiley-Blackwell, 2019)
      Background: Encapsulation of Porphyromonas gingivalis has been demonstrated as responsible of several host immunological changes, which have been associated with the pathogenesis of periodontitis. Using a murine model of ...
    • Differential human Th22-lymphocyte response triggered by Aggregatibacter actinomycetemcomitans serotypes 
      Díaz Zúñiga, Jaime; Melgar Rodríguez, Samanta; Monasterio, Gustavo; Pujol, Myriam; Rojas, Leticia; Alvarez, Carla; Carvajal, Paola; Vernal Astudillo, Rolando (Elsevier Ltd, 2017)
      Objective: In Aggregatibacter actinomycetemcomitans, different serotypes have been described based on lipopolysaccharide (LPS) antigenicity. When T lymphocytes were stimulated with these serotypes, different patterns of ...
    • Regulatory T lymphocytes in periodontitis: A translational view 
      Alvarez, Carla; Rojas Rojas, Carolina Andrea; Rojas, Leticia; Cafferata, Emilio A.; Monasterio, Gustavo; Vernal Astudillo, Rolando (Hindawi Ltd, 2018)
      Periodontitis is a chronic immuno-inflammatory disease in which the disruption of the balance between host and microbiota interactions is key to the onset and progression of the disease. The immune homeostasis associated ...
    • Serotype a of Aggregatibacter actinomycetemcomitans down-regulates the increased serotype b-induced cytokine ... 
      Rojas, Leticia; Melgar Rodríguez, Samanta; Díaz Zúñiga, Jaime; Alvarez, Carla; Monasterio, Gustavo; Rojas, Carolina; Carvajal, Paola; Vernal Astudillo, Rolando (Elsevier Ltd, 2018)
      Objective: In Aggregatibacter actinomycetemcomitans, different serotypes have been described based on LPS antigenicity. Mixed infection with the different A. actinomycetemcomitans serotypes is frequent in periodontitis ...
    • Uncoupled inflammatory, proliferative, and cytoskeletal responses in senescent human gingival fibroblasts 
      Páez, Jassir; Hernández, Romina; Espinoza, Javier; Rojas, Leticia; Martínez, Constanza E.; Tobar Bachler, Nicolás; Martínez Winkler, Jorge; Smith, Patricio C. (Wiley, 2020)
      Background and objective: Aging is characterized by a decline in tissue structure and function that may be explained by the development of cellular senescence. However, the acquisition of specific phenotypic responses in ...