Now showing items 1-6 of 6

    • Muñoz Muñoz, Orlando; Delporte, Carla; Backhouse, Nadine; Erazo, Silvia; Negrete, Rosa; Maldonado, Sergio; López Pérez, J.; San Feliciano, Arturo (2000)
      A novel cucurbitacin glycoside has been isolated from aerial parts of Kageneckia oblonga R. et P. and shown to be 3 beta-(beta-D-glucosyloxy)-16 alpha,23 alpha-epoxycucurbita-5,24-dien-11-one. The structure was established ...
    • García, Rubén; Cayunao, Cesia; Bocic, Ronny; Backhouse, Nadine; Delporte, Carla; Zaldivar, Mercedes; Erazo, Silvia (Verlag der Zeitschrift fur Naturforschung, 2005)
      Bioassay-directed fractionation for the determination of antimicrobial activity of Uncaria tomentosa, has led to the isolation of isopteropodine (0.3%), a known Uncaria pentacyclic oxindol alkaloid that exhibited antibacterial ...
    • Delporte, Carla L.; Backhouse, C. Nadine; Erazo, Silvia; Negrete, Rosa E.; Silva, Carolina; Hess, Andrés; Muñoz Muñoz, Orlando; García-Grávalos, M. Dolores; San Feliciano, Arturo (1997)
      Chilean folklore medicine uses Trevoa trinervis Miers. (Rhamnaceae), 'trevo', for the treatment of inflammation caused by wounds and burns. The antiinflammatory and antipyretic activities of crude methanol, aqueous and ...
    • Gaete, Leonardo; Tchernitchin, Andrei N.; Bustamante, Rodrigo; Villena, Joan; Ferrada, Karla; Erazo, Silvia; García, Rubén; Lemus, Igor (2010)
      The existence of multiple kinds of estrogen receptors (ERs), involved in independent groups of responses, allows their dissociation and opens the possibility to selectively induce beneficial responses but not those considered ...
    • Quaglio, Deborah; Mangoni, Maria Luisa; Stefanelli, Roberta; Corradi, Silvia; Casciaro, Bruno; Vergine, Valeria; Lucantoni, Federica; Cavinato, Luca; Cammarone, Silvia; Loffredo, Maria Rosa; Cappiello, Floriana; Calcaterra, Andrea; Erazo, Silvia; Ghirga, Francesca; Mori, Mattia; Imperi, Francesco; Ascenzioni, Fiorentina; Botta, Bruno (American Chemical Society, 2020)
      Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural ent-beyerene diterpene was identified as a promising inhibitor of the enzyme responsible ...
    • Aguirre, María C.; Delporte, Carla; Backhouse, Nadine; Erazo, Silvia; Letelier, María Eugenia; Cassels Niven, Bruce; Silva, Ximena; Alegría, Sergio; Negrete, Rosa (2006)
      Leaf extracts of Ugni molinae Turcz. are used in the Chilean cosmetic industry on the assumption that they have decongestant, regenerative, and anti-aging properties. A bioassay-guided fractionation of this plant material ...