Browsing by Author "7d29e009-610e-4a01-a01e-a794bf747736"
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ACh and ATP mediate excitatory transmission in cat carotid identified chemoreceptor units in vitro Varas, Rodrigo; Alcayaga Urbina, Julio; Iturriaga, Rodrigo (Elsevier, 2003)Several molecules have been proposed as excitatory transmitters between glomus (type 1) cells and nerve terminals of petrosal ganglion (PG) neurons in the carotid body (CB). We tested whether ACh and ATP have a role to ...
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Alcayaga Urbina, Julio; Varas, Rodrigo; Arroyo, Jorge; Iturriaga, Rodrigo; Zapata, Patricio (1999)We have recently reported that application of acetylcholine (ACh) or nicotine to the petrosal ganglion - the sensory ganglion of the glossopharyngeal nerve - elicits a burst of discharges in the carotid nerve branch, ...
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Meza, Rodrigo C.; Ortiz, Fernando C.; Bravo, Eduardo; Iturriaga-Vásquez, Patricio; Eugenín, Jaime L.; Varas, Rodrigo (2012)The carotid bodies (CBs) are chemosensory organs that respond to hypoxemia with transmitter neurosecretion, leading to a respiratory reflex response. It has been proposed that acetylcholine is a key regulator of transmitter ...
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Faundez Parraguez, Manuel; Farías Rabelo, Nicolás; González Gutiérrez, Juan Pablo; Etcheverry Berríos, Alvaro; Alzate-Morales, Jans; Adasme-Carreño, Francisco; Varas, Rodrigo; Bermudez, Isabel; Iturriaga-Vásquez, Patricio (2013)Nicotine is an agonist of nicotinic acetylcholine receptors (nAChRs) that has been extensively used as a template for the synthesis of α4β2-preferring nAChRs. Here, we used the N-methyl-pyrrolidine moiety of nicotine to ...
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Alcayaga Urbina, Julio; Varas, Rodrigo; Arroyo, Jorge; Iturriaga, Rodrigo; Zapata, Patricio (Elsevier, 1999)NaCN is a classical stimulus used to elicit discharges from carotid body chemoreceptors. The effect is assumed to be mediated by glomus (type I) cells, which release an excitatory transmitter for the excitation of carotid ...
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Alcayaga Urbina, Julio; Iturriaga, Rodrigo; Varas, Rodrigo; Arroyo, Jorge; Zapata, Patricio (1998)The petrosal ganglion innervates carotid body chemoreceptors through the carotid (sinus) nerve. These primary sensory neurons are activated by transmitters released from receptor (glomus) cells, acetylcholine (ACh) having ...