Browsing by Author "822d2cf3-c3c2-4bbf-8e9b-4a7018478411"
Now showing items 1-10 of 10
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Herrera Videla, Emilio; González Candia, Alejandro (Elsevier, 2020)
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González Candia, Alejandro (Universidad de Chile, 2019)La hipertensión pulmonar neonatal generada por hipoxia crónica perinatal es una condición fisiopatológica definida por una alterada reactividad arterial y remodelamiento vascular a nivel pulmonar. Este síndrome se ...
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Effects of melatonin on the passive mechanical response of arteries in chronic hypoxic newborn lambs Rivera, Eugenio; García Herrera, Claudio; González Candia, Alejandro; Celentano, Diego J.; Herrera Vídela, Emilio (Elsevier, 2020)Chronic hypoxia is a condition that increases the cardiovascular complications of newborns gestated and born at high altitude (HA), over 2500 m above sea level (masl). A particularly complex pathology is pulmonary arterial ...
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Aguilar, Miguel; González Candia, Alejandro; Rodríguez Borges, Jorge; Carrasco Pozo, Catalina; Canas, Daniel; García Herrera, Claudio; Herrera Videla, Emilio; Castillo Peñaloza, Rodrigo (MDPI, 2018)More than 140 million people live and works (in a chronic or intermittent form) above 2500 m worldwide and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that 55,000 persons work in high ...
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Astorga, Cristian R.; González Candia, Alejandro; Figueroa, Esteban G.; Cañas, Daniel; Ebensperger Darrouy, Germán; Reyes Catalán, Víctor; Llanos Mansilla, Jorge; Herrera Videla, Emilio; Candia, Alejandro A. (Frontiers media SA, 2018)Background: Chronic hypoxia and oxidative stress during gestation lead to pulmonary hypertension of the neonate (PHN), a condition characterized by abnormal pulmonary arterial reactivity and remodeling. Melatonin has strong ...
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González Candia, Alejandro; Candia, Alejandro A.; Figueroa, Esteban G.; Feixes, Elisenda; González Candia, Cristopher; Aguilar, Simón A.; Ebensperger, Germán; Reyes, Roberto V.; Llanos, Aníbal J.; Herrera, Emilio A. (Wiley, 2020)Pulmonary arterial hypertension of the neonate (PAHN) is a pathophysiological condition characterized by maladaptive pulmonary vascular remodeling and abnormal contractile reactivity. This is a multifactorial syndrome ...
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González Candia, Alejandro; Véliz, Marcelino; Araya, Claudio; Quezada, Sebastián; Ebensperger Darrouy, Germán; Serón Ferré, María; Reyes, Roberto V.; Llanos Mansilla, Jorge; Herrera Videla, Emilio (Mosby-Elsevier, 2016)BACKGROUND: Intrauterine growth restriction is a condition in which the fetus has a birthweight and/or length <10th percentile for the gestational age. Intrauterine growth restriction can be associated with various causes, ...
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Castillo, Rodrigo L.; Herrera Videla, Emilio; González Candia, Alejandro; Reyes Farías, Marjorie; Jara, Nicole de la; Peña, Juan Pedro; Carrasco Pozo, Catalina (Hindawi Ltd, 2018)Alterations in cardiac energy metabolism play a key role in the pathogenesis of diabetic cardiomyopathy. Hypercholesterolemia associated with bioenergetic impairment and oxidative stress has not been well characterized in ...
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Navarrete, Álvaro; Chen, Zhuoming; Aranda, Pedro; Poblete, Daniel; Utrera, Andrés; García Herrera, Claudio; González Candia, Alejandro; Beñaldo, Felipe A.; Ebensperger Darrouy, Germán; Reyes, Roberto V.; Herrera Videla, Emilio; Llanos, Aníbal J. (Frontiers Media, 2020)In this study, we assessed the effects of Atrial Natriuretic Peptide (ANP) and Cinaciguat, as experimental medicines to treat neonatal lambs exposed to chronic hypoxic conditions. To compare the different treatments, the ...
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González Candia, Alejandro; Candia Henríquez, Alejandro; Ebensperger Darrouy, Germán; Reyes, Roberto V.; Llanos, Anibal J.; Herrera Videla, Emilio (Cambridge University Press, 2020)Chronic hypoxia during gestation induces greater occurrence of perinatal complications such as intrauterine growth restriction, fetal hypoxia, newborn asphyxia, and respiratory distress, among others. This condition may ...