Browsing by Author "83a74b4e-e8f6-47e2-bb8c-77692e3b6402"

Now showing items 1-6 of 6

    • Chitosan-based delivery of avian reovirus fusogenic protein p10 gene: in vitro and in vivo studies towards ... 
      Robles Planells, Claudia; Barrera Ávalos, Carlos; Rojo, Leonel E.; Spencer, Eugenio; Cortez San Martín, Eugenio; Matiacevich, Silvia; Pavez, Jorge; Milla, Luis A.; Navarro, Franco D.; Martínez, Brandon A; Bravo, Francisco J.; Mella, Andrea; Huidobro Toro, Juan Pablo; Fernández, Ricardo; Escobar Álvarez, Alejandro; Acuña Castillo, Claudio (Hindawi, 2020)
      Reovirus is known to have an anticancer effect in both the preclinical and clinical assays. Current evidence suggests that the reovirus-mediated impact on tumor growth depends on the activation of specific antitumor immune ...
    • Chitosan-based nanoparticles for Intracellular delivery of ISAV fusion protein cDNA into melanoma cells: a ... 
      Robles Planells, Claudia; Sánchez-Guerrero, Giselle; Barrera Ávalos, Carlos; Matiacevich, Silvia; Rojo, Leonel E.; Pavéz, Jorge; Salas Huenuleo, Edison; Kogan, Marcelo J.; Escobar Álvarez, Alejandro; Milla, Luis A.; Fernández, Ricardo; Imarai, Mónica; Spencer, Eugenio; Huidobro Toro, Juan Pablo; Acuña Castillo, Claudio (Hindawi, 2020)
      Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation ...
    • Dead tumor cells expressing infectious salmon anemia virus fusogenic protein favor antigen cross-priming in vitro 
      Morales, Jonathan; Barrera Avalos, Carlos; Castro, Carlos; Castillo, Stephanie; Barrientos, Claudio; Robles Planells, Claudia; López, Ximena; Torres, Ernesto; Montoya, Margarita; Cortez San Martin, Marcelo; Riquelme, Denise; Escobar Álvarez, Alejandro; Fernández, Ricardo; Imarai, Mónica; Sauma Mahaluf, Daniela; Rojo, Leonel E.; Leiva Salcedo, Elias; Acuña Castillo, Claudio (Frontiers media SA, 2017)
      Antigen cross-presentation is a crucial step in the assembly of an antitumor immune response leading to activation of naive CD8 T cells. This process has been extensively used in clinical trials, in which dendritic cells ...
    • Metabolic syndrome and antipsychotics: The role of mitochondrial fission/fusion imbalance 
      Campo, Andrea del; Bustos, Catalina; Mascayano, Carolina; Acuña Castillo, Claudio; Troncoso, Rodrigo; Rojo, Leonel E. (Frontiers Media SA, 2018)
      Second-generation antipsychotics (SGAs) are known to increase cardiovascular risk through several physiological mechanisms, including insulin resistance, hepatic steatosis, hyperphagia, and accelerated weight gain. There ...
    • P2X7 receptor at the crossroads of T cell fate 
      Rivas Yáñez, Elizabeth; Barrera Ávalos, Carlos; Parra Tello, Brian; Briceño, Pedro F.; Rosemblatt, Mariana V.; Saavedra Almarza, Juan Pablo; Rosemblatt Silber, Mario; Acuña Castillo, Claudio; Bono Merino, María Rosa; Sauma Mahaluf, Daniela (MDPI, 2020)
      The P2X7 receptor is a ligand-gated, cation-selective channel whose main physiological ligand is ATP. P2X7 receptor activation may also be triggered by ARTC2.2-dependent ADP ribosylation in the presence of extracellular ...
    • Tolerogenic Dendritic Cells Derived from Donors with Natural Rubber Latex Allergy Modulate Allergen-Specific ... 
      Escobar Álvarez, Alejandro; Aguirre, Adam; Guzmán Meléndez, María Antonieta; González González, Rodrigo; Catalán Martina, Diego; Acuña Castillo, Claudio; Larrondo Lillo, Milton; López Nitsche, Mercedes; Pesce Reyes, Bárbara; Rolland, Jennifer; O’Hehir, Robyn; Aguillón Gutiérrez, Juan Carlos (2014)
      Natural rubber latex (NRL; Hevea brasiliensis) allergy is an IgE-mediated reaction to latex proteins. When latex glove exposure is the main sensitizing agent, Hev b 5 is one of the major allergens. Dendritic cells (DC), ...