Browsing by Author "8befedd4-e0c2-4f38-837e-cea3bbb29cb9"

Now showing items 1-3 of 3

    • GSK-3β/NFAT Signaling is involved in testosterone-induced cardiac myocyte hypertrophy 
      Durán, Javier; Oyarce Díaz, César; Pavez Giani, Mario; Valladares, Denisse; Basualto Alarcón, Carla; Lagos, Daniel; Barrientos Briones, Genaro; Troncoso Magñin, Mayarling; Ibarra, Cristián; Estrada Hormazábal, Manuel; Basualto Alarcón, Carla (Public Library Science, 2016-12-15)
      Testosterone induces cardiac hypertrophy through a mechanism that involves a concerted crosstalk between cytosolic and nuclear signaling pathways. Nuclear factor of activated Tcells (NFAT) is associated with the promotion ...
    • Mitochondrial calcium increase induced by RyR1 and IP3R channel activation after membrane depolarization ... 
      Díaz Vegas, Alexis; Córdova, A.; Valladares, Denisse; Llanos Vidal, Paola; Hidalgo, C.; Gherardi, Gaia; Stefani, Diego De; Mammucari, Cristina; Rizzuto, Rosario; Contreras Ferrat, Ariel Eduardo; Jaimovich Pérez, Enrique (Frontiers Media, 2018-06)
      Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP3-receptor (IP3R) calcium channels are necessary for the mitochondrial Ca2+ increase caused by membrane depolarization induced by potassium (or by ...
    • Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and ... 
      Altamirano, Francisco; Valladares, Denisse; Henríquez Olguín, Carlos; Casas, Mariana; López, Jose R.; Allen, Paul D.; Jaimovich Pérez, Enrique (2013)
      Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans and in mdx mice by a severe and progressive destruction of ...